Marco Lucarelli

Pubblicazioni

Titolo Pubblicato in Anno
d-mannose treatment neither affects uropathogenic Escherichia coli properties nor induces stable FimH modifications MOLECULES 2020
Vitamin K deficiency and covid-19 SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION 2020
Vitamin K deficiency and covid-19 SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION 2020
CRMS/CFSPID subjects carrying D1152H CFTR variant: can the second variant be a predictor of disease development? DIAGNOSTICS 2020
Presentation of the Consensus Document 2019 on the genetic analysis of Cystic Fibrosis.|Consensus 2019 per l'analisi genetica in Fibrosi Cistica: Presentazione del Documento BIOCHIMICA CLINICA 2020
DAT gene polymorphisms (rs28363170, rs393795) and levodopa-induced dyskinesias in Parkinson's disease NEUROSCIENCE LETTERS 2019
Trauma-exposed methyl-CpG binding protein 2 mutant mice: a new animal model for post-traumatic stress disorder ECNP workshop for early career scientists 2019
Alterations in Methyl-CpG binding protein 2 functionality provide vulnerability to traumatic events PhD national meeting, SINS 2019
Methyl-CpG binding protein 2 functional alterations provide vulnerability to develop behavioral and molecular features of post-traumatic stress disorder in male mice NEUROPHARMACOLOGY 2019
A novel splicing mutation in the ABCA1 gene, causing Tangier disease and familial HDL deficiency in a large family BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2019
CpG and non-CpG methylation in the diet-epigenetics-neurodegeneration connection CURRENT NUTRITION REPORTS 2019
Methyl-CpG binding protein 2 (MeCP2) dysfunction provides vulnerability to traumatic events in male mice 48th Meeting of the European Brain and Behaviour Society 2019
Two novel and correlated CF-causing insertions in the (TG)mTn tract of the CFTR gene PLOS ONE 2019
DNA methylation in diagnostics: State of the art and perspectives BIOCHIMICA CLINICA 2019
Active demethylation of Non-CpG moieties in animals: A neglected research area INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019
Male mice carrying dysfunctional methyl-CpG binding protein 2 are vulnerable to traumas 6th European Conference on Behaviour and Cognition 2019
Involvement of sperm acetylated histones and the nuclear isoform of Glutathione peroxidase 4 in fertilization JOURNAL OF CELLULAR PHYSIOLOGY 2018
Trans-heterozygosity for mutations enhances the risk of recurrent/chronic pancreatitis in patients with Cystic Fibrosis MOLECULAR MEDICINE 2018
Indagini genetiche di nuova generazione e terapia personalizzata: L'esempio vincente della Fibrosi Cistica BIOCHIMICA CLINICA 2018
Clinical expression of cystic fibrosis in a large cohort of Italian siblings BMC PULMONARY MEDICINE 2018

ERC

  • LS1_3
  • LS2_2
  • LS2_3
  • LS2_4
  • LS2_14
  • LS3_12
  • LS3_13

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

- regulation of DNA methylation and demethylation processes in eukaryotic cells;

- DNA methylation, modulation of gene expression and cell differentiation;

- molecular mechanisms of the gene therapy by small fragment homologous replacement (SFHR);

- molecular genetics of cystic fibrosis and of CFTR-related disorders and study of the genotype/phenotype relationship in this diseases;

- theratyping of cystic fibrosis;

- functional characterization of CFTR (cystic fibrosis transmembrane conductance regulator) and ENaC (epithelial sodium channel) genes in physiologic and pathologic conditions;

- molecular diagnostic methodologies and pathogenetic mechanisms underlying cystic fibrosis, CFTR-related disorders, atherosclerosis, alcohol addiction and neurological disorders;

- setup and automation of mutational search methodologies.

Keywords

cystic fibrosis
DNA methylation
Personalized therapy
gene editing

Progetti di Ricerca

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