Aurelia Rughetti

Pubblicazioni

Titolo Pubblicato in Anno
The prognostic impact of cancer stem-like cell biomarker aldehyde dehydrogenase-1 (ALDH1) in ovarian cancer. A meta-analysis GYNECOLOGIC ONCOLOGY 2018
The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one CANCER TREATMENT REVIEWS 2018
Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells FRONTIERS IN IMMUNOLOGY 2018
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines JOURNAL OF EXTRACELLULAR VESICLES 2018
Tumor-derived microvesicles modulate antigen cross-processing via reactive oxygen species-mediated alkalinization of phagosomal compartment in dendritic cells FRONTIERS IN IMMUNOLOGY 2017
Immunomodulatory effects of tyrosine kinase inhibitors (TKIs) in renal cell carcinoma (RCC) patients JOURNAL OF CLINICAL ONCOLOGY 2017
Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial INTERNATIONAL JOURNAL OF ONCOLOGY 2016
In normal aging ventricular system never attains pathological values of Evans' index ONCOTARGET 2016
Immunological and clinical impact of cancer stem cells in vulvar cancer: role of CD133/CD24/ABCG2-Expressing Cells ANTICANCER RESEARCH 2016
The macrophage Galactose-type C-type Lectin (MGL) modulates regulatory T cell functions PLOS ONE 2015
MGL receptor and immunity: when the ligand can make the difference JOURNAL OF IMMUNOLOGY RESEARCH 2015

ERC

  • LS1_6
  • LS2_10
  • LS2_15
  • LS4_12
  • LS6
  • LS6_3
  • LS6_10
  • LS7_14

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

  • Dendritic cells and antigen processing and presentation: extracellular vesicles and impact on tumor antigen immunogenicity and antitumor immune response
  • Role in the tumor microenvironment of Tumor glycan C-type lectin interactions: balancing immune activation and immunesuppression.
  • Target therapy and immune off target effects: Immunogenic cell death and antitumor immune response
  • Network medicine: novel approach for integrating clinical and biological data for patient outcome predictors
  • Impact of nematode A.pegreffi on antigen presenting cells function

Keywords

dendritic cells
antigen processing and presentation
Cancer vaccines
lectins
tumor antigen
Extracellular Vesicles
anti-tumor immune response
tumor microenvironment
Network medicine
glioblastoma (GBM)
breast cancer
immunogenic cell death (ICD)
ovarian cancer

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