Aurelia Rughetti

Pubblicazioni

Titolo Pubblicato in Anno
An ecofriendly iron MOF-based immunosensor for sensitive detection of vascular endothelium growth factor in serum of cancer patients NANOSCALE 2025
Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation CANCER DISCOVERY 2025
Immunological network signature of naïve non-oncogene-addicted non-small cell lung cancer patients treated with anti-PD1 therapy. A pilot study CANCERS 2025
Assuring Primary Healthcare Services to Vulnerable Children in a Disadvantaged Suburb of Rome Metropolitan City During the Pandemic: Responses to the Crisis CHILDREN 2025
MiR-326: Role and significance in brain cancers NON-CODING RNA RESEARCH 2025
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JOURNAL OF EXTRACELLULAR VESICLES 2024
CD137+ and regulatory T cells as independent prognostic factors of survival in advanced non-oncogene addicted NSCLC patients treated with immunotherapy as first-line JOURNAL OF TRANSLATIONAL MEDICINE 2024
Frequency of brain ventricular enlargement among patients with diabetes mellitus DIABETES RESEARCH AND CLINICAL PRACTICE 2024
Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma IMMUNITY 2024
Precision oncology targeting FGFRs: A systematic review on pre-clinical activity and clinical outcomes of pemigatinib CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 2024
Imperative role of adaptor proteins in macrophage toll-like receptor signaling pathways FUTURE SCIENCE OA 2024
Exploring Genomic Biomarkers for Pembrolizumab Response: A Real-World Approach and Patient Similarity Network Analysis Reveal DNA Response and Repair Gene Mutations as a Signature CANCERS 2024
Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients FRONTIERS IN IMMUNOLOGY 2024
Immune-related toxicity and soluble profile in patients affected by solid tumors: a network approach CANCER IMMUNOLOGY, IMMUNOTHERAPY 2023
Circulating CD137+ T cell levels are correlated with response to pembrolizumab treatment in advanced head and neck cancer patients INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity JOURNAL OF IMMUNOLOGY RESEARCH 2023
Proteomic characterization of extracellular vesicles released by third stage larvae of the zoonotic parasite Anisakis pegreffii (Nematoda: Anisakidae) FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 2023
Macrophage galactose-like lectin mediated interactions: investigating immunosuppressive mechanisms in glioblastoma www.siica.it 2023
Molecular mechanisms of the tyrosine kinase inhibitor pralsetinib activity in in-vitro models of medullary thyroid carcinoma: Aberrant activation of the HH-Gli signaling pathway in acquired resistance BIOMÉDECINE & PHARMACOTHÉRAPIE 2023
Sarcopenic obesity research perspectives outlined by the sarcopenic obesity global leadership initiative (SOGLI) - Proceedings from the SOGLI consortium meeting in rome November 2022 CLINICAL NUTRITION 2023

ERC

  • LS1_6
  • LS2_10
  • LS2_15
  • LS4_12
  • LS6
  • LS6_3
  • LS6_10
  • LS7_14

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

  • Dendritic cells and antigen processing and presentation: extracellular vesicles and impact on tumor antigen immunogenicity and antitumor immune response
  • Role in the tumor microenvironment of Tumor glycan C-type lectin interactions: balancing immune activation and immunesuppression.
  • Target therapy and immune off target effects: Immunogenic cell death and antitumor immune response
  • Network medicine: novel approach for integrating clinical and biological data for patient outcome predictors
  • Impact of nematode A.pegreffi on antigen presenting cells function

Keywords

dendritic cells
antigen processing and presentation
Cancer vaccines
lectins
tumor antigen
Extracellular Vesicles
anti-tumor immune response
tumor microenvironment
Network medicine
glioblastoma (GBM)
breast cancer
immunogenic cell death (ICD)
ovarian cancer

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