Valentina Noemi Madia | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2015
Structure−activity relationship of pyrrolyl diketo acid derivatives as dual Inhibitors of HIV‑1 integrase and reverse transcriptase ribonuclease H domain	JOURNAL OF MEDICINAL CHEMISTRY	2015

ERC

PE5_18

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Drug Design.

Antimicrobial agents active agains virues such as HIV, SARSCoV, HCV, CHIKV,

Antibacterial agents based on quinolone scaffold. Metallo-beta-lactamase inhibitors.

Antiprotozoals

Antifungals

Antimycobacterals

Antitumor agenst with specific mechanism of action: Kinase Inhibitors. Inhibitors of tubulin polimerization. Antitumoral agents found by phenotypic approach.

Natural substances: plant extracts for medicinal and nutraceutical applications.

Keywords

drug design and synthesis.

antiviral agents

antibacterial agents

antifungal agents

Antiprotozoal Agents

antimycobacterial agents

antitumor agents