Patrizia Gentili | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Hybrid Copper-Polyelectrolyte nanoaggregates obtained with smart block copolymers based on 4-[(hydroxyimino)aldehyde]butyl methacrylate (HIABMA) in water and acetonitrile	POLYMER	2024
Electrospray deposition of starch-containing laccase: A green technique for low-cost and eco-friendly biosensors	BIOSENSORS & BIOELECTRONICS	2024
Unusually chemoselective photocyclization of 2-(hydroxyimino)aldehydes to cyclobutanol oximes. synthetic, stereochemical, and mechanistic aspects	JOURNAL OF ORGANIC CHEMISTRY	2022
Influence of Nanoaggregation Routes on the Structure and Thermal Behavior of Multiple-Stimuli-Responsive Micelles from Block Copolymers of Oligo(ethylene glycol) Methacrylate and the Weak Acid [2-(Hydroxyimino)aldehyde]butyl Methacrylate	LANGMUIR	2022
Tailor-made alkaliphilic and thermostable fungal laccases for industrial wood processing	BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS	2022
Click-connected 2-(hydroxyimino)aldehydes for the design of UV-responsive functional molecules	EUROPEAN JOURNAL OF ORGANIC CHEMISTRY	2021
Titanium-based tetrakis-2,3-[5,6-di(substituted)pyrazino]porphyrazine. Synthesis and characterization	EUROPEAN JOURNAL OF INORGANIC CHEMISTRY	2020
Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES	2019
2‐(Hydroxyimino)aldehydes: photochemical and physico‐chemical properties of a versatile functional group for monomer design	CHEMISTRY	2018
A first study on copolymers of a methacrylate containing the 2-(hydroxyimino) aldehyde group and OEGMA. RAFT polymerization and assessment of thermal and photoresponsive polymer behavior	POLYMER CHEMISTRY	2017
Kinetics and mechanistic study of competitive inhibition of thymidinephosphorylase by 5-fluoruracil derivatives	COLLOIDS AND SURFACES. B, BIOINTERFACES	2016
Re-designing the substrate binding pocket of laccase for enhanced oxidation of sinapic acid	CATALYSIS SCIENCE & TECHNOLOGY	2016
Oxidative cleavage of 1-aryl-isochroman derivatives using the Trametes villosa laccase/1-hydroxybenzotriazole system	NEW JOURNAL OF CHEMISTRY	2016

Interessi di ricerca

2-(Idrossiimmino)aldeidi e loro applicazioni
L'attività di ricerca si concentra sullo studio delle proprietà chimico-fisiche e fotochimiche di derivati delle ossime, le 2-(idrossiimmino)aldeidi (HIA) di struttura generale R-C(=NOH)CHO.

Lo studio riguarda diversi aspetti principali: il comportamento fotochimico delle HIA, la sintesi di copolimeri multi-stimolo sensibili contenenti questo nuovo gruppo funzionale, le loro capacità di complessare ioni metallici e la possibilità di utilizzarle come profarmaci per la cura di infezioni microbiche e/o di tumori

Gruppi di ricerca

Fabrication of biosensors with electrospray deposition (ESD)/ ELECTROSPRAY DEPOSITION FOR BIOSENSING

Gruppi di ricerca - Responsabile

Sintesi di nuovi copolimeri metacrilici multi-stimolo sensibili

Sintesi di intermedi chirali per via fotochimica

Sintesi e studio di derivati delle 2-(idrossiimmino)aldeidi come precursori di radicali imminossile ed alchilici per applicazioni antimicrobiche e antitumorali

Laboratori di ricerca

Laboratorio di materiali organici stimolo sensibili