Giuseppe Giannini | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
PIK3CA somatic mutation in sinonasal teratocarcinosarcoma.	AURIS, NASUS, LARYNX	2020
Matched germline and tumor profiling in male breast cancer for the discovery of molecular subtypes with clinical relevance	Cancer ResearchCANCER RESEARCH	2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation	CELL DEATH & DISEASE	2020
A novel BRCA2 splice variant identified in a young woman	MOLECULAR GENETICS & GENOMIC MEDICINE	2020
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer	CANCERS	2019
Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer	CANCERS	2019
Next-generation sequencing of BRCA1 and BRCA2 genes for rapid detection of germline mutations in hereditary breast/ovarian cancer	PEERJ	2019
Insight into genetic susceptibility to male breast cancer by multigene panel testing: results from a multicenter study in Italy	INTERNATIONAL JOURNAL OF CANCER	2019
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP	NATURE COMMUNICATIONS	2019
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance	CANCER RESEARCH	2019
Evaluation of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk	ENDOCRINE CONNECTIONS	2019
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2	ONCOGENESIS	2019
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors	SCIENTIFIC REPORTS	2019
Identification of novel BRCA1 large genomic rearrangements by a computational algorithm of amplicon-based Next-Generation Sequencing data	PEERJ	2019
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness	CANCER RESEARCH	2019
Why the Therapeutic Impact of RAS Mutation Clearance in Plasma ctDNA Deserves to Be Further Explored in Metastatic Colorectal Cancer	FRONTIERS IN ONCOLOGY	2019
Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy	SCIENTIFIC REPORTS	2018
Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations	HUMAN MUTATION	2018
Effective treatment of a platinum-resistant cutaneous squamous cell carcinoma case by EGFR pathway inhibition	MOLECULAR AND CLINICAL ONCOLOGY	2018
Coexistence of three EGFR mutations in an NSCLC patient: A brief report	THE INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS	2018

Progetti di Ricerca

Dissecting the role of the Nijmegen breakage syndrome protein in SHH-dependent tumorigenesis
Repressing or enhancing replication stress: the two sides of the coin to understand and tackle MYCN-dependent tumors.