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stefano.gianni@uniroma1.it
Stefano Gianni
Professore Ordinario
Struttura:
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
E-mail:
stefano.gianni@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
The cooperative folding of annexin A2 relies on a transient nonnative intermediate
BIOPHYSICAL JOURNAL
2022
SH2 Domains: Folding, Binding and Therapeutical Approaches
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
A short structural extension dictates the early stages of folding of a PDZ domain
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
2022
An Outlook on the Complexity of Protein Morphogenesis in Health and Disease
FRONTIERS IN MOLECULAR BIOSCIENCES
2022
Double mutant cycles as a tool to address folding, binding, and allostery
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Folding and misfolding of a PDZ tandem repeat
JOURNAL OF MOLECULAR BIOLOGY
2021
Fuzziness and frustration in the energy landscape of protein folding, function, and assembly
ACCOUNTS OF CHEMICAL RESEARCH
2021
Probing the effects of local frustration in the folding of a multidomain protein
JOURNAL OF MOLECULAR BIOLOGY
2021
Determining folding and binding properties of the C-terminal SH2 domain of SHP2
PROTEIN SCIENCE
2021
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer
BIOLOGY DIRECT
2021
Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes
CURRENT OPINION IN STRUCTURAL BIOLOGY
2021
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Emerging therapeutic agents for colorectal cancer
MOLECULES
2021
Unveiling the molecular basis of the noonan syndrome-causing mutation T42A of SHP2
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Demonstration of binding induced structural plasticity in a sh2 domain
FRONTIERS IN MOLECULAR BIOSCIENCES
2020
Templated folding of intrinsically disordered proteins
THE JOURNAL OF BIOLOGICAL CHEMISTRY
2020
Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein
PROTEIN SCIENCE
2020
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2020
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Progetti di Ricerca
Understanding and hijacking intrinsically disordered proteins in viral infection and cancer
Targeting the oncogenic signalling adaptor proteins CRKL, GAB2 and FRS2
Understanding the mechanism of recognition between Gab2 and its physiological partners
Investigating the role of protein disorder
Targeting SHP2 and Sos1 to block Noonan Syndrome
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