Francesco Fazi | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
ID4-dependent secretion of VEGFA enhances the invasion capability of breast cancer cells and activates YAP/TAZ via integrin β3-VEGFR2 interaction	CELL DEATH & DISEASE	2024
Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress	CELL DEATH & DISEASE	2024
The lncRNAMALAT1-WTAP axis: a novel layer of EMT regulation in hypoxic triple-negative breast cancer	CELL DEATH DISCOVERY	2024
WTAP and m6A-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells	CELLULAR AND MOLECULAR LIFE SCIENCES	2024
Ferritin-based disruptor nanoparticles: A novel strategy to enhance LDL cholesterol clearance via multivalent inhibition of PCSK9–LDL receptor interaction	PROTEIN SCIENCE	2024
Understanding the crosstalk between AML cells and bone marrow stromal cells to overcome treatment resistance	ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY	2024
SEMA6C: a novel adhesion-independent FAK and YAP activator, required for cancer cell viability and growth	CELLULAR AND MOLECULAR LIFE SCIENCES	2023
Editorial: Protein homeostasis in growth, development and disease	FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY	2023
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways	CELLULAR AND MOLECULAR LIFE SCIENCES	2023
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming	MOLECULAR ASPECTS OF MEDICINE	2023
Retinoic acid and proteotoxic stress induce AML cell death overcoming stromal cell protection	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2023
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3	CANCER COMMUNICATIONS	2023
Non-coding RNAs in the crosstalk between breast cancer cells and tumor-associated macrophages	NON-CODING RNA	2022
Nucleolar localization of the ErbB3 receptor as a new target in glioblastoma	BMC MOLECULAR AND CELL BIOLOGY	2022
CD99 as a novel therapeutic target on leukemic progenitor cells in FLT3-ITDmut AML	LEUKEMIA	2022
Long Non-Coding RNAs in the Cell Fate Determination of Neoplastic Thymic Epithelial Cells	FRONTIERS IN IMMUNOLOGY	2022
MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer	COMMUNICATIONS BIOLOGY	2022
Circular RNAs activity in the leukemic bone marrow microenvironment	NON-CODING RNA	2022
Understanding ER homeostasis and the UPR to enhance treatment efficacy of acute myeloid leukemia	DRUG RESISTANCE UPDATES	2022
Polysialic acid sustains the hypoxia-induced migration and undifferentiated state of human glioblastoma cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022

ERC

LS2_3
LS3_9
LS4_11

Interessi di ricerca

- Non-coding RNA regulation of cell fate determination

- Retinoic Acid (RA) regulation of myeloid differentiation

Keywords

non-coding RNAs

ER stress

Modulation of Oxidative Stress

acute myeloid leukemia

all-trans-retinoic acid

Progetti di Ricerca

Development of novel therapeutic strategies to overcome resistance to tyrosine-kinase and bcl-2 inhibitors in FLT3-ITD+ Acute Myeloid Leukemia cells.
Impact of circulating miRNAs uptake and internalization on of EGFR signaling pathway in neoplastic cells.

Laboratori di ricerca

Meccanismi regolativi del differenziamento