Bruno Botta | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Combined Delivery of miR-15/16 through Humanized Ferritin Nanocages for the Treatment of Chronic Lymphocytic Leukemia	PHARMACEUTICS	2024
Hedgehog Pathway Inhibition by Novel Small Molecules Impairs Melanoma Cell Migration and Invasion under Hypoxia	PHARMACEUTICALS	2024
Natural Flavonoid Derivatives Have Pan-Coronavirus Antiviral Activity	MICROORGANISMS	2023
Resorc[4]arene Modifiers for Supramolecular Site-Directed Immobilization of Antibodies on Multi-Walled Carbon Nanotubes	CHEMBIOCHEM	2023
Use of elexacaftor/tezacaftor/ivacaftor combination in pregnancy	ARCHIVES OF GYNECOLOGY AND OBSTETRICS	2023
Natural Cannabichromene (CBC) Shows Distinct Scalemicity Grades and Enantiomeric Dominance in Cannabis sativa Strains	JOURNAL OF NATURAL PRODUCTS	2023
Bioactivity of the cannabigerol cannabinoid and its analogues – the role of 3-dimensional conformation	ORGANIC & BIOMOLECULAR CHEMISTRY	2023
Resorc[4]arene-Modified Gold-Decorated Magnetic Nanoparticles for Immunosensor Development	BIOCONJUGATE CHEMISTRY	2023
A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids	JOURNAL OF NATURAL PRODUCTS	2023
Selective targeting of cancer-related G-quadruplex structures by the natural compound dicentrine	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
Exploring the potential of anthraquinone-based hybrids for identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour	CHEMISTRY	2023
DEVELOPMENT OF A SECOND GENERATION OF ARNT INHIBITORS: ABIETANE-TYPE DITERPENOIDS	Book of Abstract	2023
The triprenylated anthranoid Ferruginin A, a promising scaffold for the development of novel antibiotics against Gram-positive bacteria	ANTIBIOTICS	2022
Esc peptides as novel potentiators of defective cystic fibrosis transmembrane conductance regulator: an unprecedented property of antimicrobial peptides	CELLULAR AND MOLECULAR LIFE SCIENCES	2022
Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons	SCIENTIFIC REPORTS	2022
Resorc[4]arene-functionalized MWCNTS for the development of new highly sensitive immunosensors	MedChem 2022 (XI Meeting of the Paul Ehrlich Euro-PhD Network)	2022
Resorc[4]arene-functionalized MWCNTs for the development of new highly sensitive electrochemical immunosensors	Book of Abstracts	2022
Synthesis, Biosynthesis, and Biological Activity of Diels–Alder Adducts from Morus Genus: An Update	MOLECULES	2022
Industrial Hemp (Cannabis sativa L.) Inflorescences as Novel Food: The Effect of Different Agronomical Practices on Chemical Profile	FOODS	2022
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma	CANCER LETTERS	2021

ERC

LS4_12
PE5
PE5_16
PE5_17

KET

Nanotecnologie
Life-science technologies & biotechnologies
Sustainable technologies & development

Interessi di ricerca

Isolamento, caratterizzazione di prodotti naturali da piante. Semisintesi e sintesi totale di prodotti naturali. Sintesi di macrocicli resorc[4]arenici e applicazioni. Funzionalizzazione di nanotubi di carbonio con macrocicli per applicazioni di biosensoristica. Chimica dei cannabinoidi e prodotti estratti dalla Cannabis.

Keywords

chimica

BASI BIOLOGICHE DEL CANCRO

organic chemistry

prodotti naturali

Multiwalled carbon nanotubes (MWCNTs)

biosensing

calixarene

Resorc[4]arene

Gruppi di ricerca - Responsabile

Botta Lab

Laboratori di ricerca

Botta Lab