Salta al contenuto principale
Ricerc@Sapienza
Toggle navigation
Home
Login
Home
Persone
marzia.perluigi@uniroma1.it
Marzia Perluigi
Professore Ordinario
Struttura:
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
E-mail:
marzia.perluigi@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimer’s dysmetabolism, neuropathology, and possible therapies
FREE RADICAL BIOLOGY & MEDICINE
2021
Protein oxidative damage in UV-related skin cancer and dysplastic lesions contributes to neoplastic promotion and progression
CANCERS
2020
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome
NEUROBIOLOGY OF DISEASE
2020
The anti-diabetic drug metformin rescues aberrant mitochondrial activity and restrains oxidative stress in a female mouse model of rett syndrome
JOURNAL OF CLINICAL MEDICINE
2020
Potential therapeutic value of the anti-diabetic drug metformin in a mouse model of Rett syndrome: a preclinical study
FENS 2020 virtual forum
2020
Multiple Herpes simplex virus-1 (HSV-1) reactivations induce protein oxidative damage in mouse brain. Novel mechanisms for Alzheimer’s disease progression
MICROORGANISMS
2020
Down syndrome Is a metabolic disease: altered Insulin signaling mediates peripheral and brain dysfunctions
FRONTIERS IN NEUROSCIENCE
2020
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases
CELL DEATH & DISEASE
2020
The BACH1/Nrf2 axis in brain in down syndrome and transition to alzheimer disease-like neuropathology and dementia
ANTIOXIDANTS
2020
Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention
PROGRESS IN NEUROBIOLOGY
2020
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
CELL DEATH & DISEASE
2020
The dysregulation of OGT/OGA cycle mediates Tau and APP neuropathology in down syndrome
NEUROTHERAPEUTICS
2020
Proteomics study of peripheral blood mononuclear cells in down syndrome children
ANTIOXIDANTS
2020
BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brain—Implications for neurodegeneration
ANTIOXIDANTS
2020
Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease
MOLECULAR NEUROBIOLOGY
2019
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease
NEUROBIOLOGY OF DISEASE
2019
Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE
2019
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome
REDOX BIOLOGY
2019
Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence
BRAIN PATHOLOGY
2019
Targeting mitochondria in Alzheimer disease: rationale and perspectives
CNS DRUGS
2019
« prima
< precedente
1
2
3
4
seguente ›
ultima »
Progetti di Ricerca
Defects of mitophagy and mitochondrial activity as essential determinants of Alzheimer's disease in Down Syndrome: promising therapeutic strategy
Aberrant insulin signaling contributes to development of Alzheimer disease in Down Syndrome: identifying novel drug candidates
Triplication of miR-802 contributes to aberrant Insulin signaling in Down syndrome brain
© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma