Marzia Perluigi | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models	JOURNAL OF ALZHEIMER'S DISEASE	2018
Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism	FREE RADICAL BIOLOGY & MEDICINE	2018
Poly-ubiquitin profile in Alzheimer disease brain	NEUROBIOLOGY OF DISEASE	2018
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2018
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2018
Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: novel hints on immunosenescence and biomarker detection	FREE RADICAL BIOLOGY & MEDICINE	2018
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome	TRANSLATIONAL NEURODEGENERATION	2018
mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia	FREE RADICAL BIOLOGY & MEDICINE	2018
Oxidative stress, protein modification and Alzheimer disease	BRAIN RESEARCH BULLETIN	2017
Introductory editorial: drug-eluting stents or drug-eluting grafts? insights from proteomic analysis	DRUG TARGET INSIGHTS	2017
The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein homeostasis revealed by redox proteomics	ANTIOXIDANTS & REDOX SIGNALING	2017
Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology	ANTIOXIDANTS & REDOX SIGNALING	2017
HNE-modified proteins in Down syndrome: involvement in development of Alzheimer disease neuropathology	FREE RADICAL BIOLOGY & MEDICINE	2017
I principi europei sui metodi alternativi alla sperimentazione animale	Metodi alternativi alla sperimentazione animale	2017
Metodi alternativi alla sperimentazione animale		2017
Redox proteomics: A key tool for new insights into protein modification with relevance to disease	ANTIOXIDANTS & REDOX SIGNALING	2017
From redox proteomics to clinical practice: Search for therapeutic targets	JOURNAL OF GERONTOLOGY AND GERIATRICS	2017
Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome	NEURODEGENERATIVE DISEASES	2016
Impairment of biliverdin reductase-a promotes brain insulin resistance in Alzheimer disease: a new paradigm	FREE RADICAL BIOLOGY & MEDICINE	2016
Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype	JOURNAL OF ALZHEIMER'S DISEASE	2016

Progetti di Ricerca

Defects of mitophagy and mitochondrial activity as essential determinants of Alzheimer's disease in Down Syndrome: promising therapeutic strategy
Aberrant insulin signaling contributes to development of Alzheimer disease in Down Syndrome: identifying novel drug candidates
Triplication of miR-802 contributes to aberrant Insulin signaling in Down syndrome brain