Alessia Ciogli

Pubblicazioni

Titolo Pubblicato in Anno
Synthesis and Characterization of Mitochondria-Targeted Triphenylphosphonium Bolaamphiphiles Mitochondrial Medicine 2021
Ultra-high performance separation of basic compounds on reversed-phase columns packed with fully/superficially porous silica and hybrid particles by using ultraviolet transparent hydrophobic cationic additives JOURNAL OF SEPARATION SCIENCE 2020
Sulfonamide inhibitors of beta-Catenin signaling as anticancerAgents with different output on c-Myc CHEMMEDCHEM 2020
Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2019
A silica-supported catalyst containing 9-amino-9-deoxy-9-epi-quinine and a benzoic acid derivative for stereoselective batch and flow heterogeneous reactions EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2019
Modular and conservative procedure for the quantification of amino functionalities bonded to solid porous matrices ANALYTICA CHIMICA ACTA 2019
An innovative method for quantification of basic sites linked on solid matrices Book of abstracts Merck Young Chemists’ Symposium XIX edition 2019
Synthesis of pyrano[2,3-: F] chromen-2-ones vs. pyrano[3,2-g] chromen-2-ones through site controlled gold-catalyzed annulations ORGANIC & BIOMOLECULAR CHEMISTRY 2019
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2018
Enantioselective ultra high performance liquid and supercritical fluid chromatography: the race to the shortest chromatogram JOURNAL OF SEPARATION SCIENCE 2018
Recognition mechanism of aromatic derivatives resolved by argentation chromatography: The driving role played by substituent groups ANALYTICA CHIMICA ACTA 2018
Stepwise “bridge-to-bridge” reduction of monoclonal antibodies and light chain detection: case studies of tenatumomab and trastuzumab SEPARATION SCIENCE PLUS 2018
Synthesis of bromoundecyl resorc[4]arenes and applications of the cone stereoisomer as selector for liquid chromatography JOURNAL OF ORGANIC CHEMISTRY 2018
Recent developments in chiral separations by supercritical fluid chromatography Chiral Analysis (Second Edition) 2018
Aggregation behaviour of triphenylphosphonium bolaamphiphiles JOURNAL OF COLLOID AND INTERFACE SCIENCE 2018
Unmatched kinetic performance in enantioselective supercritical fluid chromatography by combining latest generation whelk-O1 chiral stationary phases with a low-dispersion in-house modified equipment ANALYTICAL CHEMISTRY 2018
Copper-catalyzed C-N bond formation via C-H functionalization: facile synthesis of multisubstituted imidazo[1,2- a ]pyridines from N -(2-pyridinyl)enaminones SYNTHESIS 2018
Direct analysis of chiral active pharmaceutical ingredients and their counterions by ultra high performance liquid chromatography with macrocyclic glycopeptide-based chiral stationary phases JOURNAL OF CHROMATOGRAPHY A 2018
3,5-Dinitrobenzoyl-9-amino-9-deoxy-9-epiquinine as Pirkle-Anion Exchange Hybrid-Type Chiral Selector in High-Performance Liquid Chromatography CHROMATOGRAPHIA 2017

ERC

  • PE4_5
  • PE4_10
  • PE5_17

KET

  • Advanced materials
  • Sustainable technologies & development

Interessi di ricerca

L’attività scientifica è focalizzata da un lato allo studio dei processi di riconoscimento molecolare mediante cromatografia liquida ad elevate prestazioni (sintesi di fasi stazionarie di nuova generazione UHPLC e sviluppo di metodi analitici avanzati); e dall’altro, sulla completa indagine stereochimica di molecole chirali sia nel campo della chimica organica che in quello biofarmaceutico con particolare attenzione allo studio di specie stereolabili. Più recente è l'interesse verso lo studio di sistemi organocatalitici per sintesi asimmetrica mediante spettrometria di massa e il loro uso in sistemi eterogenei. 

 

Keywords

enantiomer separation
high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS–MS)
organocatalysis

Progetti di Ricerca

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