Alessia Ciogli

Pubblicazioni

Titolo Pubblicato in Anno
Capillary methacrylate-based monoliths by grafting from/to γ-ray polymerization on a tentacle-type reactive surface for the liquid chromatographic separations of small molecules and intact proteins JOURNAL OF CHROMATOGRAPHY A 2017
Tetrasubstituted cyclopentadienones as suitable enantiopure ligands with axial chirality. ORGANIC & BIOMOLECULAR CHEMISTRY 2017
Future perspectives in high efficient and ultrafast chiral liquid chromatography through zwitterionic teicoplanin-based 2-µm superficially porous particles JOURNAL OF CHROMATOGRAPHY A 2017
Chiral Separations. Chiral Dynamic Chromatography in the Study of Stereolabile Compounds Handbook of Advanced Chromatography/ Mass Spectrometry Techniques 2017
Ultra-fast high-efficiency enatioseparations by means of a teicoplanin-based chiral stationary phase made on sub-2μm totally porous silica particles of narrow size distribution JOURNAL OF CHROMATOGRAPHY A 2016
Covalently assembled resorcin[4]arenes and molecular tweezers: a chiral recognition rationale by NMR SUPRAMOLECULAR CHEMISTRY 2016
Separation of intact proteins on γ-ray-induced polymethacrylate monolithic columns: A highly permeable stationary phase with high peak capacity for capillary high-performance liquid chromatography with high-resolution mass spectrometry JOURNAL OF SEPARATION SCIENCE 2016
Experimental evidence of the kinetic performance achievable with columns packed with new 1.9 μm fully porous particles of narrow particle size distribution JOURNAL OF CHROMATOGRAPHY A 2016
Rationale behind the optimum efficiency of columns packed with new 1.9 μm fully porous particles of narrow particle size distribution JOURNAL OF CHROMATOGRAPHY A 2016
Pirkle-type chiral stationary phase on core-shell and fully porous particles: are superficially porous particles always the better choice toward ultrafast high-performance enantioseparations? JOURNAL OF CHROMATOGRAPHY A 2016
Enantiopure C1-symmetric N-heterocyclic carbene ligands from desymmetrized meso-1,2-diphenylethylenediamine: application in ruthenium-catalyzed olefin metathesis CATALYSTS 2016
Atropisomerism in 3-arylthiazolidine-2-thiones. A combined dynamic NMR and dynamic HPLC study ORGANIC & BIOMOLECULAR CHEMISTRY 2016
Expanding the potential of chiral chromatography for high-throughput screening of large compound libraries by means of sub–2μ Whelk-O 1 stationary phase in supercritical fluid conditions JOURNAL OF CHROMATOGRAPHY A 2015
Evaluation of two sub-2_m stationary phases, core-shell and totally porous monodisperse, in the second dimension of on-line comprehensive two dimensional liquid chromatography, a case study: separation of milk peptides after expiration date JOURNAL OF CHROMATOGRAPHY A 2015
Stereolability of chiral ruthenium catalysts with frozen NHC ligand conformations investigated by dynamic-HPLC CHIRALITY 2015
Organocatalytic atroposelective formal Diels-Alder desymmetrization of N -arylmaleimides ORGANIC LETTERS 2015

ERC

  • PE4_5
  • PE4_10
  • PE5_17

KET

  • Advanced materials
  • Sustainable technologies & development

Interessi di ricerca

L’attività scientifica è focalizzata da un lato allo studio dei processi di riconoscimento molecolare mediante cromatografia liquida ad elevate prestazioni (sintesi di fasi stazionarie di nuova generazione UHPLC e sviluppo di metodi analitici avanzati); e dall’altro, sulla completa indagine stereochimica di molecole chirali sia nel campo della chimica organica che in quello biofarmaceutico con particolare attenzione allo studio di specie stereolabili. Più recente è l'interesse verso lo studio di sistemi organocatalitici per sintesi asimmetrica mediante spettrometria di massa e il loro uso in sistemi eterogenei. 

 

Keywords

enantiomer separation
high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS–MS)
organocatalysis

Progetti di Ricerca

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