Alessia Ciogli

Pubblicazioni

Titolo Pubblicato in Anno
Stepwise “bridge-to-bridge” reduction of monoclonal antibodies and light chain detection: case studies of tenatumomab and trastuzumab SEPARATION SCIENCE PLUS 2018
Synthesis of bromoundecyl resorc[4]arenes and applications of the cone stereoisomer as selector for liquid chromatography JOURNAL OF ORGANIC CHEMISTRY 2018
Recent developments in chiral separations by supercritical fluid chromatography Chiral Analysis (Second Edition) 2018
Aggregation behaviour of triphenylphosphonium bolaamphiphiles JOURNAL OF COLLOID AND INTERFACE SCIENCE 2018
Unmatched kinetic performance in enantioselective supercritical fluid chromatography by combining latest generation whelk-O1 chiral stationary phases with a low-dispersion in-house modified equipment ANALYTICAL CHEMISTRY 2018
Copper-catalyzed C-N bond formation via C-H functionalization: facile synthesis of multisubstituted imidazo[1,2- a ]pyridines from N -(2-pyridinyl)enaminones SYNTHESIS 2018
Direct analysis of chiral active pharmaceutical ingredients and their counterions by ultra high performance liquid chromatography with macrocyclic glycopeptide-based chiral stationary phases JOURNAL OF CHROMATOGRAPHY A 2018
3,5-Dinitrobenzoyl-9-amino-9-deoxy-9-epiquinine as Pirkle-Anion Exchange Hybrid-Type Chiral Selector in High-Performance Liquid Chromatography CHROMATOGRAPHIA 2017
Capillary methacrylate-based monoliths by grafting from/to γ-ray polymerization on a tentacle-type reactive surface for the liquid chromatographic separations of small molecules and intact proteins JOURNAL OF CHROMATOGRAPHY A 2017
Tetrasubstituted cyclopentadienones as suitable enantiopure ligands with axial chirality. ORGANIC & BIOMOLECULAR CHEMISTRY 2017
Future perspectives in high efficient and ultrafast chiral liquid chromatography through zwitterionic teicoplanin-based 2-µm superficially porous particles JOURNAL OF CHROMATOGRAPHY A 2017
Chiral Separations. Chiral Dynamic Chromatography in the Study of Stereolabile Compounds Handbook of Advanced Chromatography/ Mass Spectrometry Techniques 2017
Ultra-fast high-efficiency enatioseparations by means of a teicoplanin-based chiral stationary phase made on sub-2μm totally porous silica particles of narrow size distribution JOURNAL OF CHROMATOGRAPHY A 2016
Covalently assembled resorcin[4]arenes and molecular tweezers: a chiral recognition rationale by NMR SUPRAMOLECULAR CHEMISTRY 2016
Separation of intact proteins on γ-ray-induced polymethacrylate monolithic columns: A highly permeable stationary phase with high peak capacity for capillary high-performance liquid chromatography with high-resolution mass spectrometry JOURNAL OF SEPARATION SCIENCE 2016
Experimental evidence of the kinetic performance achievable with columns packed with new 1.9 μm fully porous particles of narrow particle size distribution JOURNAL OF CHROMATOGRAPHY A 2016
Rationale behind the optimum efficiency of columns packed with new 1.9 μm fully porous particles of narrow particle size distribution JOURNAL OF CHROMATOGRAPHY A 2016
Pirkle-type chiral stationary phase on core-shell and fully porous particles: are superficially porous particles always the better choice toward ultrafast high-performance enantioseparations? JOURNAL OF CHROMATOGRAPHY A 2016
Enantiopure C1-symmetric N-heterocyclic carbene ligands from desymmetrized meso-1,2-diphenylethylenediamine: application in ruthenium-catalyzed olefin metathesis CATALYSTS 2016
Atropisomerism in 3-arylthiazolidine-2-thiones. A combined dynamic NMR and dynamic HPLC study ORGANIC & BIOMOLECULAR CHEMISTRY 2016

ERC

  • PE4_5
  • PE4_10
  • PE5_17

KET

  • Advanced materials
  • Sustainable technologies & development

Interessi di ricerca

L’attività scientifica è focalizzata da un lato allo studio dei processi di riconoscimento molecolare mediante cromatografia liquida ad elevate prestazioni (sintesi di fasi stazionarie di nuova generazione UHPLC e sviluppo di metodi analitici avanzati); e dall’altro, sulla completa indagine stereochimica di molecole chirali sia nel campo della chimica organica che in quello biofarmaceutico con particolare attenzione allo studio di specie stereolabili. Più recente è l'interesse verso lo studio di sistemi organocatalitici per sintesi asimmetrica mediante spettrometria di massa e il loro uso in sistemi eterogenei. 

 

Keywords

enantiomer separation
high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS–MS)
organocatalysis

Progetti di Ricerca

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