Alessia Ciogli

Pubblicazioni

Titolo Pubblicato in Anno
Stereoselectivity in electrosprayed confined volumes: asymmetric synthesis of warfarin by diamine organocatalysts in microdroplets and thin films RSC ADVANCES 2024
A C3‐Symmetric Amino Organocatalyst for Asymmetric Synthesis of Warfarin and Analogues: Mechanistic Insight from ESI‐MS Spectrometry and Computational Calculations CHEMCATCHEM 2024
SAR Analysis of Novel Coxsackie virus A9 Capsid Binders JOURNAL OF MEDICINAL CHEMISTRY 2024
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence JOURNAL OF MEDICINAL CHEMISTRY 2023
Diaryl-Pyrano-Chromenes Atropisomers: Stereodynamics and Conformational Studies MOLECULES 2023
Enantioselective catalytic Strecker reaction on cyclic (Z)-aldimines in flow: reaction optimization and sustainability aspects JOURNAL OF FLOW CHEMISTRY 2023
Theoretically Predicted and Experimentally Detected Chirality of Dibenzocyclooctynes and Their Triazole Adducts with Azides JOURNAL OF ORGANIC CHEMISTRY 2023
Synthesis of 3-substituted 2,3-dihydropyrazino[1,2-a]indol-4(1H)-ones by sequential reactions of 2-indolylmethyl acetates with α-amino acids RSC ADVANCES 2023
Assessing the performance of new chromatographic technologies for the separation of peptide epimeric impurities: the case of Icatibant EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2023
On the Nature of the Rotational Energy Barrier of Atropisomeric Hydrazides MOLECULES 2023
Primary amine catalyzed activation of carbonyl compounds: a study on reaction pathways and reactive intermediates by mass spectrometry EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2022
Resveratrol loaded in cationic glucosylated liposomes to treat Staphylococcus epidermidis infections CHEMISTRY AND PHYSICS OF LIPIDS 2022
A perspective on enantioselective chromatography by comparing ultra-high performance supercritical fluid chromatography and normal-phase liquid chromatography through the use of a Pirkle-type stationary phase TRAC. TRENDS IN ANALYTICAL CHEMISTRY 2022
Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil FOODS 2022
Accelerated D‑Fructose acid-catalyzed reactions in thin films formed by charged microdroplets deposition JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2022
Effect of natural deep eutectic solvents on trans-resveratrol photo-chemical induced isomerization and 2,4,6-trihydroxyphenanthrene electro-cyclic formation MOLECULES 2022
Preparation of a high-density vinyl silica gel to anchor cysteine via photo-click reaction and its applications in hydrophilic interaction chromatography JOURNAL OF CHROMATOGRAPHY A 2022
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Synthesis of Atropisomeric Hydrazides by One‐Pot Sequential Enantio‐ and Diastereoselective Catalysis ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 2022
A Compendium of the Principal Stationary Phases Used in Hydrophilic Interaction Chromatography: Where Have We Arrived? SEPARATIONS 2022

ERC

  • PE4_5
  • PE4_10
  • PE5_17

KET

  • Advanced materials
  • Sustainable technologies & development

Interessi di ricerca

L’attività scientifica è focalizzata da un lato allo studio dei processi di riconoscimento molecolare mediante cromatografia liquida ad elevate prestazioni (sintesi di fasi stazionarie di nuova generazione UHPLC e sviluppo di metodi analitici avanzati); e dall’altro, sulla completa indagine stereochimica di molecole chirali sia nel campo della chimica organica che in quello biofarmaceutico con particolare attenzione allo studio di specie stereolabili. Più recente è l'interesse verso lo studio di sistemi organocatalitici per sintesi asimmetrica mediante spettrometria di massa e il loro uso in sistemi eterogenei. 

 

Keywords

enantiomer separation
high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS–MS)
organocatalysis

Progetti di Ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma