Eleonora Palma

Pubblicazioni

Titolo Pubblicato in Anno
Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex ACTA NEUROPATHOLOGICA 2024
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome ANTIOXIDANTS 2023
Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models INFLAMMATION AND REGENERATION 2023
Correction: Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models INFLAMMATION AND REGENERATION 2023
Traditional and Innovative Anti-seizure Medications Targeting Key Physiopathological Mechanisms: Focus on Neurodevelopment and Neurodegeneration CURRENT NEUROPHARMACOLOGY 2023
A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 2022
Lipid mediator n-3 docosapentaenoic acid-derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G-protein-coupled receptor THE FASEB JOURNAL 2022
Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity BIOMEDICINES 2022
Classical and Unexpected Effects of Ultra-Micronized {PEA} in Neuromuscular Function BIOMOLECULES 2022
Unexpected Effect of IL-1beta on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia BRAIN SCIENCES 2022
Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study FRONTIERS IN PHARMACOLOGY 2022
Alzheimer's Disease with Epileptiform EEG Activity: Abnormal Cortical Sources of Resting State Delta Rhythms in Patients with Amnesic Mild Cognitive Impairment JOURNAL OF ALZHEIMER'S DISEASE 2022
GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β SCIENTIFIC REPORTS 2022
GABAergic neurotransmission in human tissues is modulated by cannabidiol LIFE 2022
Dissecting the molecular determinants of GABAA receptors current rundown, a hallmark of refractory human epilepsy BRAIN SCIENCES 2021
An unbalanced synaptic transmission: Cause or consequence of the amyloid oligomers neurotoxicity? INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Phytocannabinoids in neurological diseases: could they restore a physiological gabaergic transmission? INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism PARKINSONISM & RELATED DISORDERS 2020
Cannabinoids in the treatment of epilepsy: current status and future prospects NEUROPSYCHIATRIC DISEASE AND TREATMENT 2020
Creatine kinase and progression rate in amyotrophic lateral sclerosis CELLS 2020

ERC

  • LS5
  • LS5_1
  • LS5_3

Interessi di ricerca

Recent research: -Study of the basic mechanisms in human epilepsies.

-Study of ligand-gated ion channels involvement in different forms of human and experimental epilepsies.

-Study of the role of GABA in seizures and of new therapeutic approaches.

-Role of altered neurotransmission in the neurodevelopmental diseases

-Role of nicotinic acetylcholine receptors in neuromuscular diseases (i.e., ALS)

Keywords

Electrophysiology
gaba receptors
Acetylcholine receptor
drug resistant epilepsy
amyotrophic lateral sclerosis
neurodevelopmental disorders

Gruppi di ricerca

Laboratori di ricerca

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