Carlo Travaglini Allocatelli

Pubblicazioni

Titolo	Pubblicato in	Anno
Conformational and dynamic properties of the KH1 domain of FMRP and its fragile X syndrome linked G266E variant	BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS	2024
GRB2: A dynamic adaptor protein orchestrating cellular signaling in health and disease	BIOCHEMISTRY AND BIOPHYSICS REPORTS	2024
Persulfide Dioxygenase from Pseudomonas aeruginosa unveils a novel crosstalk mechanism between the bioenergetically-relevant gaseous signaling molecules nitric oxide and hydrogen sulfide	BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS	2024
Role of myristoylation in modulating PCaP1 interaction with calmodulin	PLANT PHYSIOLOGY AND BIOCHEMISTRY	2023
Rapid kinetics of calcium dissociation from plant calmodulin and calmodulin-like proteins and effect of target peptides	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS	2022
Folding Mechanism and Aggregation Propensity of the KH0 Domain of FMRP and Its R138Q Pathological Variant	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Folding characterization of the KH1 domain of FMRP, a protein involved in X-Fragile syndrome, and its pathological mutant.	33rd "A. Castellani" Meeting of PhD students in biochemical sciences abstract book	2022
The folding and aggregation properties of a single KH-domain protein: ribosome binding factor A (RbfA) from pseudomonas aeruginosa	BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS	2021
A glimpse into the structural properties of the intermediate and transition state in the folding of bromodomain 2 d2 by Φ value analysis	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2021
Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites	SCIENTIFIC REPORTS	2020
Structural and functional investigation of the small ribosomal subunit biogenesis GTPase A (RsgA) from pseudomonas aeruginosa	THE FEBS JOURNAL	2019
Mechanism of folding and binding of the n-terminal SH2 domain from SHP2	JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL	2018
Unveiling the folding mechanism of the bromodomains	BIOCHEMISTRY AND BIOPHYSICS REPORTS	2017
Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ	ONCOGENESIS	2017
Molecules that target nucleophosmin for cancer treatment: an update	ONCOTARGET	2016
Studies of cytochrome: C -551 unfolding using fluorescence correlation spectroscopy and other biophysical techniques	PHYSICAL CHEMISTRY CHEMICAL PHYSICS	2016

ERC

LS1_1
LS1_7

KET

Life-science technologies & biotechnologies

Interessi di ricerca

La attività di ricerca si sviluppa preminentemente nell'ambito della Biochimica e Biofisica delle proteine con speciale attenzione al problema del folding delle proteine (determinazione dei meccanismi di folding, caratterizzazione strutturale ed energetica degli stati di transizione e di stati intermedi tramite metodiche spettroscopiche all'equilibrio ed in cinetica rapida e super-rapida) e ai processi di misfolding (fibrillogenesi e caratterizzazione di stati amiloidi). Un altro aspetto riguarda lo studio delle interazioni intermolecolari di diversi sistemi proteici, sia procariotici che eucariotici. Metodiche utilizzate: ingegneria proteica, produzione e purificazione di proteine ricombinanti, spettroscopia, cinetica rapida.

Gruppi di ricerca

Laboratorio di biochimica e analisi strutturale