Fabio Di Domenico | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Autoantibodies profile in matching CSF and serum from AD and aMCI patients: potential pathogenic role and link to oxidative damage	CURRENT ALZHEIMER RESEARCH	2016
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients	FREE RADICAL BIOLOGY & MEDICINE	2016
Bach1 overexpression in down syndrome correlates with the alteration of the ho-1/bvr-a system: insights for transition to Alzheimer's disease	JOURNAL OF ALZHEIMER'S DISEASE	2015
Strategy to reduce free radical species in Alzheimer's disease: an update of selected antioxidants	EXPERT REVIEW OF NEUROTHERAPEUTICS	2015
Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease	RESEARCH IN CARDIOVASCULAR MEDICINE	2015
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53	JOURNAL OF NEUROSCIENCE RESEARCH	2015
Redox proteomics in human biofluids: sample preparation, separation and immunochemical tagging for analysis of protein oxidation	Systems Biology of Alzheimer's Disease	2015
Aberrant insulin signaling in Alzheimer's disease: current knowledge	FRONTIERS IN NEUROSCIENCE	2015
MTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy	NEUROBIOLOGY OF DISEASE	2015
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD	JOURNAL OF NEUROCHEMISTRY	2015

Progetti di Ricerca

Deciphering the the interplay between the unfolded protein response and insulin resistance in Down syndrome brain
Inhibition of PERK pathway for the early treatment of Alzheimer Disease-like cognitive decline in Down Syndrome
The sweet link between aberrant brain metabolism and cognitive decline: A novel role for altered protein O-GlcNAcylation.
Deciphering the role of aberrant PERK/NRF2 axis in Down Syndrome