Paolo Guglielmi


Titolo Pubblicato in Anno
Chiral Hydroxy Metabolite of Mebendazole: Analytical and Semi-Preparative High-Performance Liquid Chromatography Resolution and Chiroptical Properties PHARMACEUTICALS 2024
Novel Insights on CAI–CORM Hybrids: Evaluation of the CO Releasing Properties and Pain-Relieving Activity of Differently Substituted Coumarins for the Treatment of Rheumatoid Arthritis JOURNAL OF MEDICINAL CHEMISTRY 2023
Indoleamine 2,3-dioxygenase Metalloenzymes: from bench to bedside 2023
Kinetic Study on the Base-Catalyzed Imine-Enamine Tautomerism of a Chiral Biologically Active Isoxazoline Derivative by HPLC on Amylose Tris(3,5-dimethylphenylcarbamate) Chiral Stationary Phase MOLECULES 2023
Novel therapeutic opportunities for Toxoplasma gondii, Trichomonas vaginalis, and Giardia intestinalis infections EXPERT OPINION ON THERAPEUTIC PATENTS 2023
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration ANTIOXIDANTS 2023
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Metal-organic frameworks (MOFs) as biomolecules drug delivery systems for anticancer purposes EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2022
Treatment of Toxoplasmosis: An Insight on Epigenetic Drugs Topics in Medicinal Chemistry 2022
An updated patent review on monoamine oxidase (MAO) inhibitors EXPERT OPINION ON THERAPEUTIC PATENTS 2022
Aurone Scaffold and Structural Analogues for the Development of Monoamine Oxidase (MAO) Inhibitors Flavonoids and Phenolics 2022
Synthesis and Evaluation of Thymol-Based Synthetic Derivatives as Dual-Action Inhibitors against Different Strains of H. pylori and AGS Cell Line MOLECULES 2021
Dual carbonic anhydrase ix/xii inhibitors and carbon monoxide releasing molecules modulate LPS-mediated inflammation in mouse macrophages ANTIOXIDANTS 2021
New aspects of monoamine oxidase b inhibitors: The key role of halogens to open the golden door CURRENT MEDICINAL CHEMISTRY 2021
An innovative spectroscopic approach for qualitative and quantitative evaluation of Mb-CO from myoglobin carbonylation reaction through chemometrics methods SPECTROCHIMICA ACTA. PART A, MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 2021
High-performance liquid chromatography enantioseparation of chiral 2-(benzylsulfinyl)benzamide derivatives on cellulose tris(3,5-dichlorophenylcarbamate) chiral stationary phase JOURNAL OF CHROMATOGRAPHY A 2020
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors JOURNAL OF MEDICINAL CHEMISTRY 2020
Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2020
Antimalarial Agents from Medicinal Plant and Fungal Sources Plant-derived Bioactives. Production, Properties and Therapeutic Applications 2020
Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2020


  • PE5_18


  • Advanced materials
  • Life-science technologies & biotechnologies

Interessi di ricerca

  • Design e sintesi di inibitori delle monoaminoossidasi umane (hMAO-A / hMAO-B).
  • Design e sintesi di inibitori selettivi delle isoforme IX e XII dell’anidrasi carbonica umana (hCA IX, hCA XII) implicate nei tumori.
  • Design e sintesi di farmaci antitumorali inibitori della chinesina Eg5.
  • Sviluppo e sintesi di metal-organic frameworks (MOFs) per applicazioni biomediche.

Ulteriori interessi di ricerca:

  • Impiego delle microonde nella sintesi chimica (molecole biologicamente attive, MOF) o per estrazioni di principi attivi da matrici vegetali (MAE).
  • Estrazione, purificazione e caratterizzazione di anticorpi monoclonali da matrici vegetali.

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