Fabio Altieri

Pubblicazioni

Titolo Pubblicato in Anno
ERp57/PDIA3: new insight CELLULAR & MOLECULAR BIOLOGY LETTERS 2022
Ascorbate as a Bioactive Compound in Cancer Therapy: The Old Classic Strikes Back MOLECULES 2022
Ribosome-Directed Therapies in Cancer BIOMEDICINES 2022
β-Hexachlorocyclohexane drives carcinogenesis in the human normal bronchial epithelium cell line BEAS-2B INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
A comparative analysis of punicalagin interaction with PDIA1 and PDIA3 by biochemical and computational approaches BIOMEDICINES 2021
Tomato and olive bioactive compounds: a natural shield against the cellular effects induced by β-Hexachlorocyclohexane-activated signaling pathways MOLECULES 2021
Potentiation of low-dose doxorubicin cytotoxicity by affecting p-glycoprotein through caryophyllane sesquiterpenes in hepg2 cells: an in vitro and in silico study INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization ACS CHEMICAL BIOLOGY 2020
Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: a novel potential treatment for binge eating disorder NEUROPSYCHOPHARMACOLOGY 2020
Insights into pparγphosphorylation and its inhibition mechanism JOURNAL OF MEDICINAL CHEMISTRY 2020
Pdia3 expression in glioblastoma modulates macrophage/microglia pro-tumor activation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
β-hexachlorocyclohexane: a small molecule with a big impact on human cellular biochemistry BIOMEDICINES 2020
Influence of ellagitannins extracted by pomegranate fruit on disulfide isomerase PDIA3 activity NUTRIENTS 2019
STAT3 post-translational modifications drive cellular signaling pathways in prostate cancer cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019
Shmt2: a stat3 signaling new player in prostate cancer energy metabolism CELLS 2019
beta-HEXACHLOROCYCLOHEXANE MAY INDUCE HORMONE RESISTANCE IN PROSTATE CANCER Oral presentation 2019
Increased intake of energy-dense diet and negative energy balance in a mouse model of chronic psychosocial defeat EUROPEAN JOURNAL OF NUTRITION 2018
New insights in the antitumor effects of β-caryophyllene in breast cancer cells: The role of cannabinoid and adrenergic systems ANNALS OF ONCOLOGY 2018
Punicalagin, an active pomegranate component, is a new inhibitor of pdia3 reductase activity BIOCHIMIE 2018
STAT3, a hub protein of cellular signaling pathways, is triggered by β-hexaclorocyclohexane INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018

ERC

  • LS1

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

For several years, the main research project was the characterization of non-histone chromosomal proteins. After that the attention has been focused on nuclear protein purification and characterization, protein-protein and protein-DNA interactions.  Particular interest is addressed to the analysis of PDIA3, a  protein disulfide isomerase, and its cellular functions.  Current research cover the analysis of protein involved in signal transduction, cancer onset and progression, and oxidative stress response, as well as the screening of bioactive compounds and their impact on protein functionality.

Keywords

Signal Transduction
Modulation of Oxidative Stress
protein ligand interaction
cellular biology
bioactive compounds

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