Laura Ottini | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
PIK3CA c.3140A>G mutation in a patient with suspected Proteus Syndrome: a case report	CLINICAL CASE REPORTS	2018
The antiquity of hydrocephalus: the first full palaeo-neuropathological description	NEUROLOGICAL SCIENCES	2018
Contribution of MUTYH variants to male breast cancer risk: results from a multicenter study in Italy	FRONTIERS IN ONCOLOGY	2018
Retesting BRCA1/BRCA2 mutation negative male breast cancer patients using next generation sequencing technologies	BREAST CANCER RESEARCH AND TREATMENT	2017
Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores	JOURNAL OF CLINICAL ONCOLOGY	2017
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer	NATURE GENETICS	2017
Primary Peritoneal Serous Carcinoma in Men: A Rare and Non-BRCA-associated Entity.	ANTICANCER RESEARCH	2017
Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families	CANCER MEDICINE	2017
Male breast cancer	Breast Cancer: Innovations in Research and Management	2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer	NATURE GENETICS	2017
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer	GYNECOLOGIC ONCOLOGY	2016
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of modifiers of BRCA1/2	BREAST CANCER RESEARCH	2016
Smyd3 open & closed lock mechanism for substrate recruitment: The hinge motion of C-terminal domain inferred from μ-second molecular dynamics simulations	BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS	2016
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170	NATURE GENETICS	2016
The cancer genetics and pathology of male breast cancer	HISTOPATHOLOGY	2016
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene	CANCER	2016
The OncoArray Consortium: a network for understanding the genetic architecture of common cancers	CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION	2016
Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers	ONCOTARGET	2016
EMSY copy number variation in male breast cancers characterized for BRCA1 and BRCA2 mutations	BREAST CANCER RESEARCH AND TREATMENT	2016
Methylome profiling of BRCA-positive and BRCA-negative MBCs	EUROPEAN JOURNAL OF CANCER	2016

Progetti di Ricerca

Exploring somatic mutational landscapes of male breast cancers characterized for germline mutations in DNA repair genes.
Analysis of Tumor Mutational Burden in Male Breast Cancers characterized for germline mutations in homologous recombination genes
Exploring the transcriptional landscape of BRCA-positive and BRCA-negative male breast cancers by RNA-sequencing
Providing insights into the transcriptome profile of BRCA mutation-positive and -negative male breast cancer
New players in the Homologous Recombination pathway: investigating the role of SMYD3 in breast cancers characterized for BRCA mutation status