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rocco.palermo@uniroma1.it
Rocco Palermo
Professore Associato
Struttura:
DIPARTIMENTO DI MEDICINA MOLECOLARE
E-mail:
rocco.palermo@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic Cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024
Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey-Hailey disease
EXPERIMENTAL DERMATOLOGY
2023
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer: a novel mechanism of intrinsic drug resistance
FRONTIERS IN ONCOLOGY
2022
Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL
CANCERS
2022
When viruses cross developmental pathways
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021
Targeting notch to maximize chemotherapeutic benefits: rationale, advanced strategies, and future perspectives
CANCERS
2021
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response
ONCOGENESIS
2020
DNA damage stress: Cui prodest?
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL
FRONTIERS IN ONCOLOGY
2019
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia
ACS MEDICINAL CHEMISTRY LETTERS
2019
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance
CANCER RESEARCH
2019
PLK1 targets NOTCH1 during DNA damage and mitotic progression
THE JOURNAL OF BIOLOGICAL CHEMISTRY
2019
Notch3 contributes to T-cell leukemia growth via regulation of the unfolding protein response
The Biennial Congress of the Italian Association of cell biology and differentiation
2019
Notch signaling as a therapeutic target for acute lymphoblastic leukemia
EXPERT OPINION ON THERAPEUTIC TARGETS
2018
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.
ONCOGENESIS
2018
Targeting the ER/UPR signalling in Notch3-overexpressing T-cell acute lymphoblastic leukemia.
Atti del ABCD - Ph.D. meeting
2018
The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms
Molecular Mechanisms of Notch Signaling
2018
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog
CURRENT PHARMACEUTICAL DESIGN
2018
Potential targeted therapy for T-cell acute lymphoblastic leukemia: perturbing ER/UPR signaling via Notch3 down-regulation
Cell communication and signaling: how to turn bad language into positive one
2018
Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells
NANOMEDICINE
2017
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ERC
LS4_12
KET
Life-science technologies & biotechnologies
Keywords
Notch pathway
NF-kappa B
miRNAs
T-ALL
anti-tumor agents
epigenetic modulators
Notch inhibitors
Progetti di Ricerca
Study of the molecular mechanisms sustaining Notch3 expression in T-cell Acute Lymphoblastic Leukemia
Targeting Notch3-driven cancers by means of novel Notch3 receptor intercepting molecules
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