Giacomo Frati

Pubblicazioni

Titolo Pubblicato in Anno
Valvular and vascular calcium: the less the merrier? EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY 2024
Low-grade endotoxemia is associated with cardiovascular events in community-acquired pneumonia JOURNAL OF INFECTION 2024
Impact of heat-not-burn cigarette passive smoking on children's oxidative stress, endothelial and platelet function ENVIRONMENTAL POLLUTION 2024
NOX2 as a Biomarker of Academic Performance: Evidence from University Students during Examination ANTIOXIDANTS 2024
Towards the Fifth Pillar for the Treatment of Heart Failure with Reduced Ejection Fraction: Vericiguat in Older and Complex Patients AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS 2024
Oleuropein, a component of extra virgin olive oil, improves liver steatosis and lobular inflammation by lipopolysaccharides–tlr4 axis downregulation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024
Prediction of 30-day mortality after surgery for infective endocarditis using risk scores: Insights from a European multicenter comparative validation study AMERICAN HEART JOURNAL 2024
Comparative effects of different antiplatelet strategies in carriers of CYP2C19 loss-of-function alleles: a network meta-analysis EUROPEAN HEART JOURNAL. CARDIOVASCULAR PHARMACOTHERAPY 2024
Antiphospholipid Syndrome: Insights into Molecular Mechanisms and Clinical Manifestations JOURNAL OF CLINICAL MEDICINE 2024
Exposure to serum from exclusive heated tobacco product smokers induces mTOR activation and fibrotic features in human cardiac stromal cells BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE 2024
Exploring the landscape of academic retractions in medicine: a comprehensive umbrella review. MINERVA MEDICA 2024
Atrial natriuretic peptide (ANP) modulates stress-induced autophagy in endothelial cells BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2024
Association Between NOX2-Mediated Oxidative Stress, Low-Grade Endotoxemia, Hypoalbuminemia, and Clotting Activation in COVID-19 ANTIOXIDANTS 2024
Different oxidative stress and inflammation patterns of diseased left anterior descending coronary artery versus internal thoracic artery ANTIOXIDANTS 2024
Mitophagy modulation for the treatment of cardiovascular diseases EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2024
Management of acute chest pain in the Emergency Department: benefits of coronary computed tomography angiography THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 2024
Stenosing crohn's disease patients display gut autophagy/oxidative stress imbalance. OPEN ACCESS SCIENTIFIC REPORTS 2024
Toll-Like Receptor 4-Dependent Platelet-Related Thrombosis in SARS-CoV-2 Infection CIRCULATION RESEARCH 2023
The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart ELIFE 2023
Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies ANTIOXIDANTS 2023

ERC

  • LS4_10
  • LS7_2
  • LS7_4
  • LS9_3

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Meccanismi cellulari e molecolari correlati ad Autofagia e Stress Ossidativo nelle principali cardiomiopatie (ischemica, sovraccarico, valvolare, invecchiamento); Meccanismi cellulari e molecolari correlati con fenomeni di ripopolazione/rigenerazione cellulare vascolare o muscolare cardiaca post-infarto Meccanismi cellulari e molecolari correlati con la progressione dell’ipertrofia cardiaca Rivascolarizzazione coronarica: dai fattori prognostico-molecolari alla valutazione delle metodologie cliniche-interventistiche-chirurgiche Patogenesi dei fenomeni aterosclerotici e terapie antiossidanti in patologia cardiovascolare Rigenerazione cardiaca mediante l’utilizzo di cellule staminali in associazione all’ingegneria tissutale Terapia genica basata su sistemi cellulari e ruolo della Nox2 nel danno polmonare da ischemia-riperfusione acuta: nuovi strumenti per la medicina rigenerativa (EVLP) Metodologie diagnostiche applicate alle principali malattie cardiovascolari ed alla medicina rigenerativa (Ecocardiografia 3D, MRI, TC, FMT, Bioluminescenza, Fotoacustica) Metodologie, tecniche e revisione critica in ambito cardiochirurgico e cardiologico interventistico (Meta-analisi, Network Meta-analisi)

Keywords

oxidative stress, platelets, atherosclerosi
atherosclerotic plaque
coronary heart disease (chd
cardiac progenitor cell
cardiac surgery
cardiology and cardiovascular medicin
mechanistic target of rapamycin (mTOR
NADPH oxidase

Gruppi di ricerca - Responsabile

Laboratori di ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma