Giacomo Frati


Titolo Pubblicato in Anno
Toll-Like Receptor 4-Dependent Platelet-Related Thrombosis in SARS-CoV-2 Infection CIRCULATION RESEARCH 2023
The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart ELIFE 2023
Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies ANTIOXIDANTS 2023
NPPA/atrial natriuretic peptide is an extracellular modulator of autophagy in the heart AUTOPHAGY 2023
Unsupervised Machine Learning with Cluster Analysis in Patients Discharged after an Acute Coronary Syndrome: Insights from a 23,270-Patient Study THE AMERICAN JOURNAL OF CARDIOLOGY 2023
Remodeled eX vivo muscle engineered tissue improves heart function after chronic myocardial ischemia SCIENTIFIC REPORTS 2023
Polymorphic variants at NDUFC2, encoding a mitochondrial complex I subunit, associate with cardiac hypertrophy in human hypertension MOLECULAR MEDICINE 2023
An overview of sport participation and exercise prescription in mitral valve disease JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE 2023
Different Techniques of Surgical Left Atrial Appendage Closure and Their Efficacy: A Systematic Review REVIEWS IN CARDIOVASCULAR MEDICINE 2023
Is it the time for direct oral anticoagulants in bioprosthetic heart valves? EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY 2023
Del Nido cardioplegia for cardiac surgery requiring cardiopulmonary bypass: is the best yet to come? JOURNAL OF CARDIOVASCULAR MEDICINE 2023
MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation CELLULAR AND MOLECULAR LIFE SCIENCES 2023
Dark Chocolate Intake Positively Modulates Gut Permeability in Elite Football Athletes: A Randomized Controlled Study NUTRIENTS 2023
Effect of traditional or heat-not-burn cigarette smoking on circulating miRNAs in healthy subjects EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2023
Appraising features and outlook of women and men discharged after an acute coronary syndrome: evidence from the 23,700-patient PRAISE International Registry PANMINERVA MEDICA 2023
Age-related electrocardiographic characteristics of male junior soccer athletes FRONTIERS IN CARDIOVASCULAR MEDICINE 2022
The dynamic facets of the cardiac stroma. Fom classical markers to omics and translational perspectives AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress CELL DEATH DISCOVERY 2022
An Overview of the Molecular Mechanisms Associated with Myocardial Ischemic Injury: State of the Art and Translational Perspectives CELLS 2022
Aging-Related Decline of Autophagy in Patients with Atrial Fibrillation—A Post Hoc Analysis of the ATHERO-AF Study ANTIOXIDANTS 2022


  • LS4_10
  • LS7_2
  • LS7_4
  • LS9_3


  • Life-science technologies & biotechnologies

Interessi di ricerca

Meccanismi cellulari e molecolari correlati ad Autofagia e Stress Ossidativo nelle principali cardiomiopatie (ischemica, sovraccarico, valvolare, invecchiamento); Meccanismi cellulari e molecolari correlati con fenomeni di ripopolazione/rigenerazione cellulare vascolare o muscolare cardiaca post-infarto Meccanismi cellulari e molecolari correlati con la progressione dell’ipertrofia cardiaca Rivascolarizzazione coronarica: dai fattori prognostico-molecolari alla valutazione delle metodologie cliniche-interventistiche-chirurgiche Patogenesi dei fenomeni aterosclerotici e terapie antiossidanti in patologia cardiovascolare Rigenerazione cardiaca mediante l’utilizzo di cellule staminali in associazione all’ingegneria tissutale Terapia genica basata su sistemi cellulari e ruolo della Nox2 nel danno polmonare da ischemia-riperfusione acuta: nuovi strumenti per la medicina rigenerativa (EVLP) Metodologie diagnostiche applicate alle principali malattie cardiovascolari ed alla medicina rigenerativa (Ecocardiografia 3D, MRI, TC, FMT, Bioluminescenza, Fotoacustica) Metodologie, tecniche e revisione critica in ambito cardiochirurgico e cardiologico interventistico (Meta-analisi, Network Meta-analisi)


oxidative stress, platelets, atherosclerosi
atherosclerotic plaque
coronary heart disease (chd
cardiac progenitor cell
cardiac surgery
cardiology and cardiovascular medicin
mechanistic target of rapamycin (mTOR
NADPH oxidase

Gruppi di ricerca - Responsabile

Laboratori di ricerca

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