Giacomo Frati


Titolo Pubblicato in Anno
Toll-Like Receptor 4-Dependent Platelet-Related Thrombosis in SARS-CoV-2 Infection CIRCULATION RESEARCH 2023
The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart ELIFE 2023
Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies ANTIOXIDANTS 2023
NPPA/atrial natriuretic peptide is an extracellular modulator of autophagy in the heart AUTOPHAGY 2023
Unsupervised Machine Learning with Cluster Analysis in Patients Discharged after an Acute Coronary Syndrome: Insights from a 23,270-Patient Study THE AMERICAN JOURNAL OF CARDIOLOGY 2023
The dynamic facets of the cardiac stroma. Fom classical markers to omics and translational perspectives AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress CELL DEATH DISCOVERY 2022
An Overview of the Molecular Mechanisms Associated with Myocardial Ischemic Injury: State of the Art and Translational Perspectives CELLS 2022
Aging-Related Decline of Autophagy in Patients with Atrial Fibrillation—A Post Hoc Analysis of the ATHERO-AF Study ANTIOXIDANTS 2022
Current knowledge on the association between cardiovascular and periodontal disease: an umbrella review MINERVA CARDIOLOGY AND ANGIOLOGY 2022
Platelet activation favours NOX2-mediated muscle damage in elite athletes. yhe role of cocoa-derived polyphenols NUTRIENTS 2022
Is Smoking Cessation the Best Intervention Ever to Prevent Heart Failure? JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 2022
Mitochondria and doxorubicin-induced cardiomyopathy. A complex interplay CELLS 2022
Progressive stages of dysmetabolism are associated with impaired biological features of human cardiac stromal cells mediated by the oxidative state and autophagy JOURNAL OF PATHOLOGY 2022
Human platelet lysate‐derived extracellular vesicles enhance angiogenesis through miR‐126 CELL PROLIFERATION 2022
Modified risk tobacco products and cardiovascular repair: still very smoky CURRENT STEM CELL RESEARCH & THERAPY 2022
Sex-Related Differences in Oxidative, Platelet, and Vascular Function in Chronic Users of Heat-not-Burn vs. Traditional Combustion Cigarettes ANTIOXIDANTS 2022
Cardiovascular effects of COVID-19 lockdown in professional football players PANMINERVA MEDICA 2022
Impact of weather and pollution on the rate of cerebrovascular events in a large metropolitan area PANMINERVA MEDICA 2022
Unequal opportunities in Italian cardiovascular research. Focus on gender PANMINERVA MEDICA 2022


  • LS4_10
  • LS7_2
  • LS7_4
  • LS9_3


  • Life-science technologies & biotechnologies

Interessi di ricerca

Meccanismi cellulari e molecolari correlati ad Autofagia e Stress Ossidativo nelle principali cardiomiopatie (ischemica, sovraccarico, valvolare, invecchiamento); Meccanismi cellulari e molecolari correlati con fenomeni di ripopolazione/rigenerazione cellulare vascolare o muscolare cardiaca post-infarto Meccanismi cellulari e molecolari correlati con la progressione dell’ipertrofia cardiaca Rivascolarizzazione coronarica: dai fattori prognostico-molecolari alla valutazione delle metodologie cliniche-interventistiche-chirurgiche Patogenesi dei fenomeni aterosclerotici e terapie antiossidanti in patologia cardiovascolare Rigenerazione cardiaca mediante l’utilizzo di cellule staminali in associazione all’ingegneria tissutale Terapia genica basata su sistemi cellulari e ruolo della Nox2 nel danno polmonare da ischemia-riperfusione acuta: nuovi strumenti per la medicina rigenerativa (EVLP) Metodologie diagnostiche applicate alle principali malattie cardiovascolari ed alla medicina rigenerativa (Ecocardiografia 3D, MRI, TC, FMT, Bioluminescenza, Fotoacustica) Metodologie, tecniche e revisione critica in ambito cardiochirurgico e cardiologico interventistico (Meta-analisi, Network Meta-analisi)


oxidative stress, platelets, atherosclerosi
atherosclerotic plaque
coronary heart disease (chd
cardiac progenitor cell
cardiac surgery
cardiology and cardiovascular medicin
mechanistic target of rapamycin (mTOR
NADPH oxidase

Gruppi di ricerca - Responsabile

Laboratori di ricerca

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