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francesca.fabretti@uniroma1.it
Francesca Fabretti
Assegnista di ricerca
Struttura:
DIPARTIMENTO DI SCIENZE MEDICO-CHIRURGICHE E DI MEDICINA TRASLAZIONALE
E-mail:
francesca.fabretti@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors
NEOPLASIA
2023
The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond
CANCERS
2023
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
NEUROPATHOLOGY & APPLIED NEUROBIOLOGY
2022
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors
ONCOGENE
2021
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer
FRONTIERS IN ONCOLOGY
2020
Zoledronic acid in a mouse model of human fibrous dysplasia: ineffectiveness on tissue pathology, formation of “giant osteoclasts” and pathogenetic implications
CALCIFIED TISSUE INTERNATIONAL
2020
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2
ONCOGENESIS
2019
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors
SCIENTIFIC REPORTS
2019
Identification of novel BRCA1 large genomic rearrangements by a computational algorithm of amplicon-based Next-Generation Sequencing data
PEERJ
2019
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors
CELL DEATH & DISEASE
2018
Progetti di Ricerca
La risposta al danno del DNA come bersaglio per il trattamento del Medulloblastoma con deregolazione di MYCN
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