Pubblicazioni

MAO inhibitors and their wider applications: a patent review

2018 - EXPERT OPINION ON THERAPEUTIC PATENTS

Carradori, Simone; Secci, Daniela; Petzer, Jacques P.

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Loubidi, Mohammed; Jouha, Jabrane; Tber, Zahira; Khouili, Mostafa; Suzenet, Franck; Akssira, Mohamed; Erdogan, MÃ¼min Alper; KÃ¶se, Fadime AydÄ±n; DagcÄ±, Taner; Armagan, GÃ¼liz; Saso, Luciano; Guillaumet, GÃ©rald

9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2

2018 - MEDICINAL CHEMISTRY

ApplovÃ¡, Lenka; VeljoviÄ, Elma; MuratoviÄ, Samija; KarlÃÄkovÃ¡, Jana; MacÃ¡kovÃ¡, KateÅina; ZavrÅ¡nik, Davorka; Saso, Luciano; DuriÄ, Kemal; MladÄnka, PÅemysl

Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts

2018 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Krasilnikova, Jelena; Lauberte, Liga; Stoyanova, Elena; Abadjieva, Desislava; Chervenkov, Mihail; Mori, Mattia; De Paolis, Elisa; Mladenova, Vanya; Telysheva, Galina; Botta, Bruno; Kistanova, Elena

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

Leveraging the cruzain S3 subsite to increase affinity for reversible covalent inhibitors

2018 - BIOORGANIC CHEMISTRY

Cianni, Lorenzo; Sartori, Geraldo; Rosini, Fabiana; De Vita, Daniela; Pires, Gabriel; Lopes, Bianca Rebelo; LeitÃ£o, Andrei; Burtoloso, Antonio C B; Montanari, Carlos A

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae Î±- and Î²-class enzymes

2018 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Bua, Silvia; Berrino, Emanuela; Del Prete, Sonia; Murthy, Vallabhaneni S; Vijayakumar, Vijayaparthasarathi; Tamboli, Yasinalli; Capasso, Clemente; Cerbai, Elisabetta; Mugelli, Alessandro; Carta, Fabrizio; Supuran, Claudiu T