Pubblicazioni

Enzyme kinetics and inhibition of histone acetyltransferase KAT8

2015 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Wapenaar, Hannah; van der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J.

A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach

2015 - JOURNAL OF MEDICINAL CHEMISTRY

Milite, Ciro; Feoli, Alessandra; Sasaki, Kazuki; La Pietra, Valeria; Balzano, Amodio Luca; Marinelli, Luciana; Mai, Antonello; Novellino, Ettore; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca

A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

2015 - ONCOTARGET

De Luca, Anastasia; ROTILI, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; MAI, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria

New insights on the mechanism of quinoline-based DNA methyltransferase inhibitors

2015 - THE JOURNAL OF BIOLOGICAL CHEMISTRY

Gros, Christina; Fleury, Laurence; Nahoum, Virginie; Faux, CÃ©line; Valente, Sergio; Labella, Donatella; Cantagrel, FrÃ©dÃ©ric; Rilova, Elodie; Bouhlel, Mohamed Amine; David Cordonnier, Marie HÃ©lÃ¨ne; Dufau, Isabelle; Ausseil, FrÃ©dÃ©ric; Mai, Antonello; Mourey, Lionel; Lacroix, Laurent; Arimondo, Paola B.

Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF

2015 - CHEMMEDCHEM

Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Mai, Antonello; Novellino, Ettore; Tosco, Alessandra; Sbardella, Gianluca