My research focuses on understanding how the immune system detects and controls cancer cells, particularly in the context of cellular senescence and stress responses. By investigating the molecular mechanisms that regulate immune surveillance, we aim to identify new strategies to enhance immune recognition and clearance of cancer cells.

Current Funding

• Exploring the potential of ADAR1 as a new immunotherapeutic target in cervical cancer
  (AIRC Project IG 2021 – ID 25680)

Di Marcotullio Lab website: 

sites.google.com/uniroma1.it/dimarcotulliolab/home

CMGU - GG Lab website: 

https://sites.google.com/uniroma1.it/giannini-lab/home

Measuring operators’ cognitive and emotional states, training progresses, and teamwork is really innovative, especially in operative and real contexts. The Neuroscience Lab develops methodologies able to measure humans' mental states like mental workload, stress, attention, fatigue in real time.

Prof. Fimia carries out his research actiivity at the “Cell Stress Biology” laboratory of Department of Molecular Medicine, as well as at the Cell Biology and Electron Microscopy lab of the National Institute for Infectious Diseases (INMI) L. Spallanzani in Rome,
where the Prof. Fimia has part of his research group to carry out research activity on the basis of a formal Collaborative Agreement. 

Lab website: https://sites.google.com/uniroma1.it/emculab-canettieri

Our laboratory is interested in understanding how epigenetic and metabolic reprogramming influence tumor behaviour and to invetigate the possibility to target these alterations for therapeutic purposes.

The current main topics of our lab are:

1) Energy and redox rewiring in Cancer

Prof. Carmine Mancone is the director of the Tumor Microenvironment Research Group. This group works on understanding the molecular basis of the interaction between cancer cells and the tumor microenvironment (TME) in liver and biliary tract carcinomas.

Caratterizzazione molecolare ed epidemiologica dei virus respiratori; il contributo della risposta immune dell’ospite alla patogenesi e alle sequele respiratorie.

The early research conducted by Antonelli was focused on elucidating the in vivo and in vitro mechanisms regulating the production and activity of interferons during viral infections. His research group currently investigates the role of innate immunity, as well as the pathogenesis, diagnosis, and control of several viral infections, including HIV, HCV, major respiratory viruses (such as SARS-CoV-2, RSV, and influenza viruses), and HPV.