Alessandro Paiardini | Ricerc@Sapienza

Publications

Title	Published on	Year
L- Arginine in Pseudomonas aeruginosa controls c-di-GMP levels and biofilm formation	efb 2021	2021
Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer	ONCOGENE	2021
Phosphorylation, mg‐adp, and inhibitors differentially shape the conformational dynamics of the a‐loop of aurora‐a	BIOMOLECULES	2021
Pha-680626 is an effective inhibitor of the interaction between aurora-a and n-myc	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2021
From parp1 to tnks2 Inhibition: a structure-based approach	ACS MEDICINAL CHEMISTRY LETTERS	2020
Artemisinin derivatives with antimelanoma activity show inhibitory effect against human dna topoisomerase 1	ACS MEDICINAL CHEMISTRY LETTERS	2020
SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase	EMBO REPORTS	2020
A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome	DERMATOLOGY ONLINE JOURNAL	2020
Insights into pparγphosphorylation and its inhibition mechanism	JOURNAL OF MEDICINAL CHEMISTRY	2020
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity	CELL DEATH & DISEASE	2020
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1	CELL REPORTS	2020
A single center retrospective review of patients from central italy tested for melanoma predisposition genes	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2020
PyMod 3: a complete suite for structural bioinformatics in PyMOL	BIOINFORMATICS	2020
Structure and function of HD-GYP phosphodiesterases	Microbial Cyclic Di-Nucleotide Signaling	2020
A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome	DERMATOLOGY ONLINE JOURNAL	2020
The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism	NUCLEIC ACIDS RESEARCH	2019
N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia	FRONTIERS IN ONCOLOGY	2019
A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies	MOLECULAR GENETICS AND METABOLISM	2019
R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features	THE FEBS JOURNAL	2019
Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy-Walker malformation.	MOLECULAR GENETICS & GENOMIC MEDICINE	2019

ERC

LS1
LS1_8
LS1_12
LS1_14
LS2_11

KET

Big data & computing
Life-science technologies & biotechnologies

Interessi di ricerca

Progetti di Ricerca

MODULATING THE MITOTIC KINASE FUNCTION OF AURORA-A WITH PROTEIN-PROTEIN INTERACTION INHIBITORS

Gruppi di ricerca

Nutrient sensing and redox transducers in bacterial biofilm.