Alessandro Paiardini | Ricerc@Sapienza

Publications

Title	Published on	Year
Revisiting the “satisfaction of spatial restraints” approach of MODELLER for protein homology modeling	PLOS COMPUTATIONAL BIOLOGY	2019
Corrigendum to “Pyridoxine-5′-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g > A (P.·Arg116gln) mutation” [Mol. Genet. Metab. 122/1–2 (2017) 135–142]	MOLECULAR GENETICS AND METABOLISM	2018
Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations	IUBMB LIFE	2018
Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes	ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS	2018
Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa	THE FEBS JOURNAL	2018
The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells	THE FEBS JOURNAL	2018
A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa	PROTEINS	2018
Cysteine 180 is a redox sensor modulating activity of human pyridoxal 5'-phosphate histidine decarboxylase	BIOCHEMISTRY	2018
Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2018
Familial hypomagnesaemia, Hypercalciuria and Nephrocalcinosis associated with a novel mutation of the highly conserved leucine residue 116 of Claudin 16 in a Chinese patient with a delayed diagnosis: A case report	BMC NEPHROLOGY	2018
Identification of small molecule inhibitors of the aurora-A/TPX2 complex	ONCOTARGET	2017
Glucose metabolism in the progression of prostate cancer	FRONTIERS IN PHYSIOLOGY	2017
Pyridoxine-5'-phosphate oxidase (pnpo) deficiency. clinical and biochemical alterations associated with the c.347g>a (pp. arg116gln) mutation	MOLECULAR GENETICS AND METABOLISM	2017
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis	SCIENTIFIC REPORTS	2017
Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO)	DATA IN BRIEF	2017
Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis	SCIENTIFIC REPORTS	2017
Discovering selective diguanylate cyclase inhibitors: From PleD to discrimination of the active site of cyclic-di-GMP phosphodiesterases	c-di-GMP signaling	2017
Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ	ONCOGENESIS	2017
A novel germline mutation in CDK4 codon 24 associated to familial melanoma	CLINICAL GENETICS	2017
PyMod 2.0: improvements in protein sequence-structure analysis and homology modeling within PyMOL	BIOINFORMATICS	2017

ERC

LS1
LS1_8
LS1_12
LS1_14
LS2_11

KET

Big data & computing
Life-science technologies & biotechnologies

Interessi di ricerca

Progetti di Ricerca

MODULATING THE MITOTIC KINASE FUNCTION OF AURORA-A WITH PROTEIN-PROTEIN INTERACTION INHIBITORS

Gruppi di ricerca

Nutrient sensing and redox transducers in bacterial biofilm.