Ricerc@Sapienza

Background A retrospective study was conducted to evaluate sphincter function and quality of life (QoL) in
patients treated with radiotherapy and concurrent chemotherapy (CRT) for anal canal cancer.
Materials and Methods From 1998 to 2010, patients with anal canal cancer treated with CRT were eligible.
Radiation dose was 59.4 Gy (1.8 Gy/ fraction) and the chemotherapy regimen was 5-fluorouracil and mitomycin
C. Anorectal function was investigated by anorectal manometry and transrectal ultrasound. QoL was assessed

Objective
To review studies assessing the efficacy of occupational therapy interventions on quality of life in patients with Parkinson's disease.

Introduction
. The clinical, social, and economic implications of Parkinson’s disease (PD) are significant; disability occurs leading to a low quality of life (QoL). Information on the QoL of patients with PD and studies on the relationship between QoL and motor and cognitive function are necessary for both research and clinical use to make informed decisions in healthcare and rehabilitation. The aim of this study was to determine which scales are most used to assess QoL in patients with PD.

Background: Positivity is a general tendency to react to life experiences in a positive way, a pervasive optimistic view of oneself, one’s life, and one’s future, associated with greater positive affection and lower functional impairments. The aim of the study was to examine the role of positivity in predicting the length of hospitalization in patients operated of thoracic surgery and physical and mental health in patients born with Anorectal Malformations (ARM).

Background: Reliable Fertility-specific QoL measures can be obtained through the FertiQoL, a questionnaire with six-subscales that consider different core aspects of the person’s wellbeing and way of behaving during treatment. Objective: Examine the psychometric properties of all six-subscales of the Italian FertiQoL in a sample of infertile women and explore the effects of the ART treatment phases. Method: 323 women, in three different treatment stages (Diagnostic, Stimulation, Transfer), completed the FertiQoL.

Massage therapy is an important element of rehabilitation in the treatment of chronic low back pain (CLBP). The objective of this study was to determine the relative efficacy of massage therapy between traditional massage and a new massage approach for CLBP. We also examined whether any reduction in pain was linked to interoceptive awareness and parasympathetic activation.

Objectives: The aim of this study was to evaluate the effectiveness of modified McCall culdoplasty or Shull suspension in preventing vaginal vault prolapse after vaginal hysterectomy and the long-term impact on quality of life and sexual function. Study design: Retrospective analysis in 414 patients underwent vaginal hysterectomy for pelvic organ prolapse (POP) and vaginal suspension through modified McCall culdoplasty (group A) or Shull suspension (group B) was evaluated. Clinical features and concomitant surgical procedures were assessed.

The aim of this study was to assess the effectiveness of ospemifene in the improvement of sexual function in postmenopausal women with vulvovaginal atrophy (VVA) affected by overactive bladder syndrome (OAB) or urge urinary incontinence (UUI). One hundred five postmenopausal patients with VVA affected by OAB and/or UUI were enrolled for the study. All patients received ospemifene 60 mg for 12 weeks. Clinical examination, 3-d voiding diary and the vaginal health index (VHI) were performed at baseline and at 12 weeks. Patients completed the OAB-Q SF, FSFI, FSDS, and SF-36 questionnaires.

Endometrial cancer currently represents the most frequent gynecologic malignancy in Western countries, and the seventh most common cancer in women. For advanced-stage disease, the recurrence risk is high, and the site of the relapse is heterogeneous with localized or spread peritoneal disease. There are few therapeutic strategies, and the quality of life is poor.

Urinary incontinence, the involuntary loss of urine, is a common condition that affects approximately 50% of adult women. This condition increases with age, affecting 10% to 20% of all women and up to 77% of elderly women residing in nursing homes.