Agostino Tafuri

Pubblicazioni

Titolo Pubblicato in Anno
Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells ONCOTARGET 2017
A population-based study on myelodysplastic syndromes in the Lazio Region (Italy), medical miscoding and 11-year mortality follow-up. The Gruppo Romano-Laziale Mielodisplasie experience of retrospective multicentric registry MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES 2017
Preclinical antileukemia activity of tramesan. A newly identified bioactive fungal metabolite OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2017
Aggressive lymphomas of the elderly .the DEVEC metronomic chemotherapy schedule fits the unfit BRITISH JOURNAL OF HAEMATOLOGY 2017
Critical Roles of EGFR family members in breast cancer and breast cancer stem cells: Targets for therapy CURRENT PHARMACEUTICAL DESIGN 2016
Essential Thrombocythemia: A Comparison of Overall and Thrombosis Free Survival in Two Discrete Periods of the First Decade of 2000. a Retrospective Analysis BLOOD 2016
Pulmonary Infections in Patients with Myelodysplastic Syndromes Receiving Azacytidine Treatment BLOOD 2016
Erratum: The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia SCIENTIFIC REPORTS 2016
An increase in hemoglobin, platelets and white blood cells levels by iron chelation as single treatment in multitransfused patients with myelodysplastic syndromes: clinical evidences and possible biological mechanisms ANNALS OF HEMATOLOGY 2015
Allogeneic Transplant in Acute Myeloid Leukemia (AML) According to the Policy of the Rome Transplant Network (RTN): An Intention-to-Treat Analysis BONE MARROW TRANSPLANTATION 2015
Peripherally Inserted Central Catheter (PICC) Power Groshong 5 Fr device for management of peripheral blood stem cell collection and transplantation in haematological patients: a single centre study from the Rome Transplant Network BONE MARROW TRANSPLANTATION 2015
Unique Chemotherapy Based Reduced Intensity Conditioning Regimen for Patients Transplanted from HLA Identical Siblings, Haploidentical or Volunteer Unrelated Donors: a Prospective Study from the Rome Transplant Network BONE MARROW TRANSPLANTATION 2015
PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression ONCOTARGET 2015
Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia ONCOTARGET 2015
Targeting the leukemia cell metabolism by the CPT1a inhibition. functional pre-clinical effects in leukemias BLOOD 2015
The tissue inhibitor of metalloproteinases 1 increases the clonogenic efficiency of human hematopoietic progenitor cells through CD63/PI3K/Akt signaling EXPERIMENTAL HEMATOLOGY 2015
The pan-class I PI3 kinase inhibitor, NVP-BKM120, demonstrates anti-leukemic activity in acute myeloid leukemia HAEMATOLOGICA 2015
Severe and prolonged myelosuppression during concomitant temozolomide and radiotherapy treatment in a patient with glioblastoma multiforme INTERNATIONAL JOURNAL OF MEDICAL AND PHARMACEUTICAL CASE REPORTS 2015
Application of the International Prognostic Score of Thrombosis for Essential Thrombocytemia(ET) (IPSET-Thrombosis) in a Cohort of ET Patients: Experience from Gruppo Laziale for Myeloproliferative Ph Negative Neoplasms BLOOD 2015
Chronic phase chronic myeloid leukemia patients who failed interferon alpha and switched to imatinib: Long-term 9-year follow-up of 134 patients. AMERICAN JOURNAL OF HEMATOLOGY 2015

ERC

  • LS1_9
  • LS2_15
  • LS3_1
  • LS3_5
  • LS4_11

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Studio dei meccanismi di resistenza della cellula leucemica ed identificazione del ruolo patogenetico e prognostico di profili aberranti proteomici e metabolomici implicati nei meccanismi proliferativi ed apoptotici. Sviluppo preclinico di molecole sperimentali con potenziale ruolo terapeutico target-specifico nelle onco-emopatie. Studio dei profili proteomici e metabolomici in cellule staminali  emopoietiche umane normali e nella controparte leucemica. 

Keywords

Acute leukemia
molecular targeted therapies
drug resistance
cell signaling
cell metabolism

Progetti di Ricerca

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