Sergio Valente

Pubblicazioni

Titolo Pubblicato in Anno
Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene HUMAN GENETICS 2020
Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization ACS CHEMICAL BIOLOGY 2020
Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells ACS MEDICINAL CHEMISTRY LETTERS 2020
The innovative potential of statins in cancer: new targets for new therapies FRONTIERS IN CHEMISTRY 2020
Properly substituted cyclic Bis-(2-bromobenzylidene) compounds behaved as dual p300/CARM1 Inhibitors and Induced apoptosis in cancer cells MOLECULES 2020
CDK9 as a valuable target in cancer: from natural compounds inhibitors to current treatment in pediatric soft tissue sarcomas FRONTIERS IN PHARMACOLOGY 2020
Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity CHEMMEDCHEM 2020
Identification of novel quinazoline derivatives as potent antiplasmodial agents EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2019
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2019
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells CLINICAL EPIGENETICS 2019
Sirtuins as drug targets Epigenetic Drug Discovery 2019
Epigenetic Pharmacology in Regenerative Medicine (Epi-Drugs) Epigenetics and Regeneration 2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype CLINICAL EPIGENETICS 2019
Lysine methyltransferases and their inhibitors Chemical Epigenetics 2019
The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells SCIENTIFIC REPORTS 2019
Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo MOLECULAR NEUROBIOLOGY 2019
Statins and histone deacetylase inhibitors affect lamin A/C - histone deacetylase 2 interaction in human cells FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2019
Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer CURRENT OPINION IN CHEMICAL BIOLOGY 2019
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors NATURE COMMUNICATIONS 2018
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal OPEN ACCESS SCIENTIFIC REPORTS 2018

Progetti di Ricerca

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