Sergio Valente


Titolo Pubblicato in Anno
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors NATURE COMMUNICATIONS 2018
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal OPEN ACCESS SCIENTIFIC REPORTS 2018
Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice NEUROSCIENCE 2018
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells PHILOSOPHICAL TRANSACTIONS - ROYAL SOCIETY. BIOLOGICAL SCIENCES 2018
Trends of LSD1 inhibitors in viral infections FUTURE MEDICINAL CHEMISTRY 2018
Combined HAT/EZH2 modulation leads to cancer-selective cell death ONCOTARGET 2018
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia ONCOTARGET 2018
Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers PSYCHOPHARMACOLOGY 2018
Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS AGING CELL 2018
A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy MOLECULAR CANCER THERAPEUTICS 2018
Six years (2012-2018) of researches on catalytic EZH2 inhibitors: the boom of the 2-pyridone compounds THE CHEMICAL RECORD 2018
Application of Small Epigenetic Modulators in Pediatric Medulloblastoma FRONTIERS IN PEDIATRICS 2018
Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase CHEMMEDCHEM 2017
Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2017
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy CLINICAL EPIGENETICS 2017
EZH2 inhibitors: a patent review (2014-2016) EXPERT OPINION ON THERAPEUTIC PATENTS 2017
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells ONCOTARGET 2017
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice NEUROSCIENCE LETTERS 2017
Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model AUTOIMMUNITY 2016
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent JOURNAL OF MEDICINAL CHEMISTRY 2016

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