Sergio Valente


Titolo Pubblicato in Anno
Combined HAT/EZH2 modulation leads to cancer-selective cell death ONCOTARGET 2018
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia ONCOTARGET 2018
Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers PSYCHOPHARMACOLOGY 2018
Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS AGING CELL 2018
A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy MOLECULAR CANCER THERAPEUTICS 2018
Six years (2012-2018) of researches on catalytic EZH2 inhibitors: the boom of the 2-pyridone compounds THE CHEMICAL RECORD 2018
Application of Small Epigenetic Modulators in Pediatric Medulloblastoma FRONTIERS IN PEDIATRICS 2018
Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase CHEMMEDCHEM 2017
Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2017
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy CLINICAL EPIGENETICS 2017
EZH2 inhibitors: a patent review (2014-2016) EXPERT OPINION ON THERAPEUTIC PATENTS 2017
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells ONCOTARGET 2017
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice NEUROSCIENCE LETTERS 2017
Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model AUTOIMMUNITY 2016
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent JOURNAL OF MEDICINAL CHEMISTRY 2016
LSD1 inhibitors: a patent review (2010-2015) EXPERT OPINION ON THERAPEUTIC PATENTS 2016
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells JOURNAL OF MEDICINAL CHEMISTRY 2016
DNA methyltransferases Inhibitors from natural sources CURRENT TOPICS IN MEDICINAL CHEMISTRY 2016
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation FUTURE MEDICINAL CHEMISTRY 2016
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells. MEDCHEMCOMM 2015

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