Sergio Valente


Titolo Pubblicato in Anno
LSD1 inhibitors: a patent review (2010-2015) EXPERT OPINION ON THERAPEUTIC PATENTS 2016
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells JOURNAL OF MEDICINAL CHEMISTRY 2016
DNA methyltransferases Inhibitors from natural sources CURRENT TOPICS IN MEDICINAL CHEMISTRY 2016
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation FUTURE MEDICINAL CHEMISTRY 2016
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells. MEDCHEMCOMM 2015
Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2015
Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies ACS MEDICINAL CHEMISTRY LETTERS 2015
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2015
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells JOURNAL OF MEDICINAL CHEMISTRY 2015
Discovery of inhibitors for the ether lipid-generating enzyme AGPS as anti-cancer agents ACS CHEMICAL BIOLOGY 2015
Emerging approaches for histone deacetylase inhibitor drug discovery EXPERT OPINION ON DRUG DISCOVERY 2015
Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas CANCER RESEARCH 2015
Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity EUROPEAN NEUROPSYCHOPHARMACOLOGY 2015
Targeting lysine deacetylases (KDACs) in parasites PLOS NEGLECTED TROPICAL DISEASES 2015
New insights on the mechanism of quinoline-based DNA methyltransferase inhibitors THE JOURNAL OF BIOLOGICAL CHEMISTRY 2015

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