Gianluca Canettieri

Pubblicazioni

Titolo Pubblicato in Anno
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module CELL REPORTS 2020
Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization EXPERIMENTAL AND THERAPEUTIC MEDICINE 2020
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i CANCERS 2020
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer FRONTIERS IN ONCOLOGY 2020
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response ONCOGENESIS 2020
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth MOLECULAR ONCOLOGY 2020
Nanotechnology-based strategies to develop new anticancer therapies BIOMOLECULES 2020
Sulfonamide inhibitors of beta-Catenin signaling as anticancerAgents with different output on c-Myc CHEMMEDCHEM 2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation CELL DEATH & DISEASE 2020
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation INTERNATIONAL JOURNAL OF ONCOLOGY 2019
Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents ACS MEDICINAL CHEMISTRY LETTERS 2019
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer CANCERS 2019
Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells INTERNATIONAL JOURNAL OF ONCOLOGY 2019
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP NATURE COMMUNICATIONS 2019
Polyamine metabolism as a therapeutic target in hedgehog-driven basal cell carcinoma and medulloblastoma CELLS 2019
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 ONCOGENESIS 2019
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors SCIENTIFIC REPORTS 2019
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis NATURE COMMUNICATIONS 2018
The antioxidant, aged garlic extract, exerts cytotoxic effects on wild-type and multidrug-resistant human cancer cells by altering mitochondrial permeability INTERNATIONAL JOURNAL OF ONCOLOGY 2018
Targeting metabolic vulnerabilities to treat Shh medulloblastoma INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2018

ERC

  • LS4_9
  • LS4_12

KET

  • Life-science technologies & biotechnologies

Keywords

Colorectal cancer
Medulloblastoma
cancer metabolism
Hedgehog (Hh) pathway
epigenetic
redox imbalance
biguanides
polyamine metabolism
translation
gene transcription
AMPK
C-Myc

Gruppi di ricerca - Responsabile

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