Salta al contenuto principale
Ricerc@Sapienza
Toggle navigation
Home
Login
Home
Persone
gianluca.canettieri@uniroma1.it
Gianluca Canettieri
Professore Ordinario
Struttura:
DIPARTIMENTO DI MEDICINA MOLECOLARE
E-mail:
gianluca.canettieri@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability
CANCERS
2023
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation
CANCER LETTERS
2023
Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation
CELLS
2022
Bovine serum amine oxidase and polyamine analogues: chemical synthesis and biological evaluation integrated with molecular docking and 3-D QSAR studies
JOURNAL OF CHEMICAL INFORMATION AND MODELING
2022
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
NEUROPATHOLOGY & APPLIED NEUROBIOLOGY
2022
Opposite effect of thyroid hormones on oxidative stress and on mitochondrial respiration in COVID-19 patients
ANTIOXIDANTS
2022
The Mechanism of Action of Biguanides: New Answers to a Complex Question
CANCERS
2022
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2022
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
2022
Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021
Enzymatic spermine metabolites induce apoptosis associated with increase of p53, caspase-3 and miR-34a in both neuroblastoma cells, SJNKP and the N-Myc-amplified form IMR5
CELLS
2021
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors
ONCOGENE
2021
Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
ELIFE
2021
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids
CELL DEATH & DISEASE
2021
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module
CELL REPORTS
2020
Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization
EXPERIMENTAL AND THERAPEUTIC MEDICINE
2020
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i
CANCERS
2020
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer
FRONTIERS IN ONCOLOGY
2020
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response
ONCOGENESIS
2020
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth
MOLECULAR ONCOLOGY
2020
1
2
3
seguente ›
ultima »
ERC
LS4_9
LS4_12
KET
Life-science technologies & biotechnologies
Keywords
Colorectal cancer
Medulloblastoma
cancer metabolism
Hedgehog (Hh) pathway
epigenetic
redox imbalance
biguanides
polyamine metabolism
translation
gene transcription
AMPK
C-Myc
Progetti di Ricerca
Targeting Reductive Stress-GDF15 Axis in Colorectal Cancer
Role of IRES-dependent translation of MYC in Colorectal Cancer
Laboratori di ricerca
BIOENERGETICA
Laboratorio biochimico biologico - camera fredda
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 209
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 227 228
© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma