Gianluca Canettieri | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation	ONCOGENE	2024
Structuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene delivery	NATURE COMMUNICATIONS	2024
Development of N-(4-(1 H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability	JOURNAL OF MEDICINAL CHEMISTRY	2024
Annotation and automated segmentation of single-molecule localisation microscopy data	JOURNAL OF MICROSCOPY	2024
SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation	CELL DEATH DISCOVERY	2024
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability	CANCERS	2023
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation	CANCER LETTERS	2023
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent	ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE	2023
Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment. From synthesis to in vitro studies on neuroblastoma cell lines	JOURNAL OF COLLOID AND INTERFACE SCIENCE	2023
KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors	NEOPLASIA	2023
Modeling myotonic dystrophy type 2 using Drosophila melanogaster	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma	CELL DEATH AND DIFFERENTIATION	2023
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells	JOURNAL OF MEDICINAL CHEMISTRY	2023
Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation	CELLS	2022
Bovine serum amine oxidase and polyamine analogues: chemical synthesis and biological evaluation integrated with molecular docking and 3-D QSAR studies	JOURNAL OF CHEMICAL INFORMATION AND MODELING	2022
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma	NEUROPATHOLOGY & APPLIED NEUROBIOLOGY	2022
Opposite effect of thyroid hormones on oxidative stress and on mitochondrial respiration in COVID-19 patients	ANTIOXIDANTS	2022
The Mechanism of Action of Biguanides: New Answers to a Complex Question	CANCERS	2022
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2022
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor	JOURNAL OF MEDICINAL CHEMISTRY	2022