Pubblicazioni

In silico and in vitro analysis of major cannabis-derived compounds as fatty acid amide hydrolase inhibitors

2021 - MOLECULES

Criscuolo, E.; De Sciscio, M. L.; Fezza, F.; Maccarrone, M.

Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies

2021 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Baglini, E; Ravichandran, R; Berrino, E; Salerno, S; Barresi, E; Marini, Am; Viviano, M; Castellano, S; Da Settimo, F; Supuran, Ct; Cosconati, S; Taliani, S.

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 integrase and reverse transcriptase associated ribonuclease H inhibitors

2020 - ANTIVIRAL RESEARCH

Esposito, F.; Sechi, M.; Pala, N.; Sanna, A.; Koneru, P. C.; Kvaratskhelia, M.; Naesens, L.; Corona, A.; Grandi, N.; di Santo, R.; D'Amore, V. M.; Di Leva, F. S.; Novellino, E.; Cosconati, S.; Tramontano, E.

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Rotondi, G.; Guglielmi, P.; Carradori, S.; Secci, D.; De Monte, C.; De Filippis, B.; Maccallini, C.; Amoroso, R.; Cirilli, R.; Akdemir, A.; Angeli, A.; Supuran, C. T.

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

2015 - BIOORGANIC & MEDICINAL CHEMISTRY

Consalvi, Sara; Alfonso, Salvatore; Di Capua, Angela; Poce, Giovanna; Pirolli, Adele; Sabatino, Manuela; Ragno, Rino; Anzini, Maurizio; Sartini, Stefania; La Motta, Concettina; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Biava, Mariangela