Enostosis, hyperostosis corticalis generalisata and possible overlap syndrome in a 7000 years old mummy from Libya
Multidisciplinary study of a 7000 years old naturally mummified body from SW Libya reveals different pathologies.
radiology
Myocardial blood flow estimates from dynamic contrast-enhanced magnetic resonance imaging: three quantitative methods
Dynamic contrast-enhanced cardiovascular magnetic resonance imaging can be used to quantitatively assess the myocardial blood ow (MBF), recovering the tissue impulse response function for the transit of a gadolinium bolus through the myocardium. Several deconvolution techniques are available, using various models for the impulse response. The method of choice
Diabetes and pancreatic neuroendocrine tumours: which interplays, if any?
Pancreatic neuroendocrine tumours (PanNETs) represent an uncommon type of pancreatic neoplasm, whose incidence is increasing worldwide. As per exocrine pancreatic cancer, a relationship seems to exist between PanNETs and glycaemic alterations. Diabetes mellitus (DM) or impaired glucose tolerance often occurs in PanNET patients as a consequence of hormonal hypersecretion by the tumour, specifically affecting glucose metabolism, or due to tumour mass effects.
Evaluating the incidence of pathological complete response in current international rectal cancer practice. The barriers to widespread safe deferral of surgery
Introduction: The mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR) rate and the reliability of detecting a cCR by conventional pre-operative imaging. Methods: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed.