Progetti di ricerca
| Titolo del progetto | Anno | Proponente | Abstract | ERC | Keywords | Struttura |
|---|---|---|---|---|---|---|
| EXERCISE CAPACITY IMPAIRMENT IN HYPERTROPHYC CARDIOMYOPATHY. UNDERLYING MECHANISMS, CLINICAL CORRELATES AND PROGNOSTIC VALUE. | 2017 | Damiano Magri' |
Hypertrophic cardiomyopathy (HCM), the most common inherited cardiovascular disease (1:500), is usually characterized by markedly heterogeneous morphologic, functional, and clinical spectra. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Symptomatic critical carotid stenosis. Effects of oxidative stress on immune response | 2017 | Maurizio Taurino |
Reactive oxygen species (ROS) are a family of small reactive molecules containing oxygen. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Osteocalcina: nuovo marcatore di rigidità arteriosa in pazienti affetti da Diabete Mellito tipo 1 | 2017 | Carmen Mignogna |
L'osteocalcina (OC), prodotta dagli osteoblasti, promuove la mineralizzazione ossea. Recentemente è stato individuato un suo ruolo endocrino sull'omeostasi glucidica ed endoteliale. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Antineoplastic Effect of Combined Treatment Mitotane/Ionizing Radiations in a Xenograft Model of Adrenocortical Carcinoma: a Preclinical Study | 2017 | Antonio Stigliano |
Mitotane (MTT) is an adrenolytic drug most used in the adjuvant and advanced treatment of adrenocortical carcinoma (ACC). |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Neoplastic progression of solid tumors and lymphomas. | 2017 | Andrea Vecchione |
The research interest of our group is focused on the pathogenetic mechanisms involved in development and progression of solid tumors and lymphoproliferative diseases. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Hypertension and cardiovascular fibrosis: role of p66Shc in aldosterone-induced fibrosis | 2017 | Carmine Savoia |
p66Shc has classically been implicated in cellular responses to oxidative stress and redox-sensitive processes associated with aging and longevity. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Targeting lipid metabolism to enhance immunogenicity of Cancer Stem Cells | 2017 | Rita Mancini |
Alterations in lipid- and cholesterol-associated pathways are widely described in tumor cells. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Significato prognostico e correlati clinici della ripolarizzazione precoce in una coorte di pazienti affetti da cardiomiopatia ipertrofica | 2017 | Pietro Francia |
La ripolarizzazione precoce (ERP) o J wave è un pattern elettrocardiografico di comune riscontro in soggetti giovani, sani, e atleti. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| Role of FGFR2b and its PKC-mediated signaling in the regulation of epithelial cell diffentiation. | 2017 | Francesca Belleudi |
FGFR2b is the FGFR2 epithelial splicing variant whose signaling triggers different outcomes in epithelial cells, including differentiation. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE | |
| STUDY ON THE ROLE OF HHV-6 IN microRNAs DISREGULATION IN CELIAC DISEASE | 2017 | Laura Mazzuti |
Celiac disease (CD) is an autoimmune disorder induced, in genetically predisposed subjects, by the ingestion of gluten. |
name | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |