Giacomo Frati

Pubblicazioni

Titolo Pubblicato in Anno
Lipopolysaccharide induces platelet activation in HIV patients: the role of different viral load patterns HIV MEDICINE 2021
Von Willebrand factor with increased binding capacity is associated with reduced platelet aggregation but enhanced agglutination in COVID-19 patients: another COVID-19 paradox? JOURNAL OF THROMBOSIS AND THROMBOLYSIS 2021
The role of antioxidants supplementation in clinical practice: focus on cardiovascular risk factors ANTIOXIDANTS 2021
Beneficial effects of a combination of natural product activators of autophagy on endothelial cells and platelets BRITISH JOURNAL OF PHARMACOLOGY 2021
3D morphometric analysis of ascending aorta as an adjunctive tool to predict type A acute aortic dissection JOURNAL OF THORACIC DISEASE 2021
Impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation. The SUR-VAPES Chronic Study THORAX 2021
Trehalose, a natural disaccharide, reduces stroke occurrence in the stroke-prone spontaneously hypertensive rat PHARMACOLOGICAL RESEARCH 2021
Role of oxidative stress and autophagy in thoracic aortic aneurysms JACC. BASIC TO TRANSLATIONAL SCIENCE 2021
Effects of experimental interventions to improve the biomedical peer-review process. A systematic review and meta-analysis JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE 2021
Baseline, procedural and outcome features of patients undergoing transcatheter aortic valve implantation according to different body mass index categories MINERVA MEDICA 2021
An interplay between UCP2 and ROS protects cells from high-salt-induced injury through autophagy stimulation CELL DEATH & DISEASE 2021
A snapshot global survey on side effects of COVID-19 vaccines among healthcare professionals and armed forces with a focus on headache PANMINERVA MEDICA 2021
Left atrial appendage exclusion in atrial fibrillation radiofrequency ablation during mitral valve surgery: a single-center experience CARDIOLOGY RESEARCH AND PRACTICE 2021
H9c2 Cardiomyocytes under Hypoxic Stress: Biological Effects Mediated by Sentinel Downstream Targets OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2021
Oxidative stress in the pathogenesis of antiphospholipid syndrome. Implications for the atherothrombotic process ANTIOXIDANTS 2021
Circulating lipopolysaccharides and impaired antioxidant status in patients with atrial fibrillation. data from the athero-af study FRONTIERS IN CARDIOVASCULAR MEDICINE 2021
Interplay between COVID-19, pollution, and weather features on changes in the incidence of acute coronary syndromes in early 2020 INTERNATIONAL JOURNAL OF CARDIOLOGY 2021
Impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation. the SUR-VAPES Chronic Study THORAX 2021
A novel signalling mechanism regulating telomere length in cardiomyocytes CARDIOVASCULAR RESEARCH 2021
Low-grade endotoxaemia enhances artery thrombus growth via Toll-like receptor 4: implication formyocardial infarction EUROPEAN HEART JOURNAL 2020

ERC

  • LS4_10
  • LS7_2
  • LS7_4
  • LS9_3

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Meccanismi cellulari e molecolari correlati ad Autofagia e Stress Ossidativo nelle principali cardiomiopatie (ischemica, sovraccarico, valvolare, invecchiamento); Meccanismi cellulari e molecolari correlati con fenomeni di ripopolazione/rigenerazione cellulare vascolare o muscolare cardiaca post-infarto Meccanismi cellulari e molecolari correlati con la progressione dell’ipertrofia cardiaca Rivascolarizzazione coronarica: dai fattori prognostico-molecolari alla valutazione delle metodologie cliniche-interventistiche-chirurgiche Patogenesi dei fenomeni aterosclerotici e terapie antiossidanti in patologia cardiovascolare Rigenerazione cardiaca mediante l’utilizzo di cellule staminali in associazione all’ingegneria tissutale Terapia genica basata su sistemi cellulari e ruolo della Nox2 nel danno polmonare da ischemia-riperfusione acuta: nuovi strumenti per la medicina rigenerativa (EVLP) Metodologie diagnostiche applicate alle principali malattie cardiovascolari ed alla medicina rigenerativa (Ecocardiografia 3D, MRI, TC, FMT, Bioluminescenza, Fotoacustica) Metodologie, tecniche e revisione critica in ambito cardiochirurgico e cardiologico interventistico (Meta-analisi, Network Meta-analisi)

Keywords

oxidative stress, platelets, atherosclerosi
atherosclerotic plaque
coronary heart disease (chd
cardiac progenitor cell
cardiac surgery
cardiology and cardiovascular medicin
mechanistic target of rapamycin (mTOR
NADPH oxidase

Gruppi di ricerca - Responsabile

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