Rino Ragno

Pubblicazioni

Titolo Pubblicato in Anno
Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Teaching and learning computational drug design: student investigations of 3D quantitative structure–activity relationships through web applications JOURNAL OF CHEMICAL EDUCATION 2020
Essential oils and their main chemical components: the past 20 years of preclinical studies in melanoma CANCERS 2020
Antimicrobial essential oil formulation: chitosan coated nanoemulsions for nose to brain delivery PHARMACEUTICS 2020
Essential oils biofilm modulation activity, chemical and machine learning analysis. Application on staphylococcus aureus isolates from cystic fibrosis patients INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7 MOLECULES 2020
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-6 MOLECULES 2020
The anti-STAT1 polyphenol myricetin inhibits M1 microglia activation and counteracts neuronal death THE FEBS JOURNAL 2020
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2019
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones JOURNAL OF MEDICINAL CHEMISTRY 2019
In-vitro evaluation of different antimicrobial combinations with and without colistin against carbapenem-resistant acinetobacter baumannii MOLECULES 2019
Machine learning analyses on data including essential oil chemical composition and in vitro experimental antibiofilm activities against Staphylococcus species. MOLECULES 2019
Breakthroughs in medicinal chemistry: new targets and mechanisms, new drugs, new hopes-4 MOLECULES 2019
Variation in essential oil content and composition of Ridolfia segetum Moris based on 30-hour prolonged fractionated extraction procedure NATURAL PRODUCT RESEARCH 2019
Chemical composition and antimicrobial activity of essential oil of Helichrysum italicum (Roth) G. Don fil. (Asteraceae) from Montenegro NATURAL PRODUCT RESEARCH 2019
Shmt2: a stat3 signaling new player in prostate cancer energy metabolism CELLS 2019
Breakthroughs in medicinal chemistry: new targets and mechanisms, New Drugs, New Hopes-5 MOLECULES 2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype CLINICAL EPIGENETICS 2019
www.3d-qsar.com: a web portal that brings 3-D QSAR to all electronic devices—the Py-CoMFA web application as tool to build models from pre-aligned datasets JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 2019
Garze pre-medicate con idrogel e idrolato di Citrus aurantium var amara (fiori) per la prevenzione delle infezioni microbiche della cute lesa NATURAL 1 2019

ERC

  • LS1_13
  • LS2_11
  • PE4_13
  • PE5_18

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Design of small molecules as potential bioactive agents

Developing of methods to predict the activity of new molecules

Machine learning applications to develop model for complex mixtures

Keywords

drug design
drug design and discovery
computational chemistry
essential oil active components (EO-ACs)
essential oil
Molecular docking
drug repurposing
quantitative composition-activity relationships

Progetti di Ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma