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luigi.scipione@uniroma1.it
Luigi Scipione
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
luigi.scipione@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Pyrrolyl pyrazoles as non-diketo acid inhibitors of the HIV-1 ribonuclease H function of reverse transcriptase
ACS MEDICINAL CHEMISTRY LETTERS
2020
In vitro antiviral activity of new oxazoline derivatives as potent poliovirus inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
2019
Searching for new agents active against candida albicans biofilm: a series of indole derivatives, design, synthesis and biological evaluation
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2019
Design, synthesis, and biological evaluation of new 1-(aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents
JOURNAL OF MEDICINAL CHEMISTRY
2019
Comparison of different methods for the extraction of cannabinoids from cannabis
NATURAL PRODUCT RESEARCH
2019
Towards a new application of amaranth seed oil as an agent against Candida albicans
NATURAL PRODUCT RESEARCH
2019
Tegaserod for the treatment of Irritable Bowel syndrome
ANTI-INFLAMMATORY & ANTI-ALLERGY AGENTS IN MEDICINAL CHEMISTRY
2019
Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studies
MEDCHEMCOMM
2018
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2018
Novel benzazole derivatives endowed with potent antiheparanase activity
JOURNAL OF MEDICINAL CHEMISTRY
2018
Novel symmetrical benzazolyl derivatives endowed with potent anti-heparanase activity
JOURNAL OF MEDICINAL CHEMISTRY
2018
New deferiprone derivatives as multi-factorial cholinesterase inhibitors: design, synthesis and in vitro evaluation
Eurasia
2018
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2017
Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase
CHEMMEDCHEM
2017
Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2017
New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2017
New indole derivatives against C. albicans biofilm
ESOC
2017
In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2016
Discovery of in vitro antitubercular agents through in silico ligand-based approaches
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2016
Diaryl disulfides as novel stabilizers of tumor suppressor Pdcd4
PLOS ONE
2016
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Progetti di Ricerca
Progettazione e sintesi di esteri fenil-etil-imidazolici come nuovi inibitori del CYP51 di Naegleria fowleri, attivi nella meningoencefalite amebica primaria (PAM)
Multitarget directed ligands approach per lo sviluppo di nuovi potenziali agenti nella terapia del morbo di Alzheimer.
Sviluppo di nuovi multitarget directed ligands come potenziali agenti nella terapia del morbo di Alzheimer.
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