Luigi Scipione | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2017
New indole derivatives against C. albicans biofilm	ESOC	2017
In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2016
Discovery of in vitro antitubercular agents through in silico ligand-based approaches	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2016
Diaryl disulfides as novel stabilizers of tumor suppressor Pdcd4	PLOS ONE	2016
New N,N-dimethylcarbamate inhibitors of acetylcholinesterase: design synthesis and biological evaluation	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2016
Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS	2016
Efficient synthesis of 3,5-dicarbamoyl-1,4-dihydropyridines from pyridinium salts. Key molecules in understanding NAD(P)+/NAD(P)H pathways	JOURNAL OF HETEROCYCLIC CHEMISTRY	2015
Design, synthesis and evaluation of 3,4-dihydroxybenzoic acid derivatives as antioxidants, bio-metal chelating agents and acetylcholinesterase inhibitors	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2015
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2015
N‑substituted quinolinonyl diketo acid derivatives as HIV integrase strand transfer inhibitors and their activity against RNase H function of reverse transcriptase	JOURNAL OF MEDICINAL CHEMISTRY	2015
Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2015
Structure−activity relationship of pyrrolyl diketo acid derivatives as dual Inhibitors of HIV‑1 integrase and reverse transcriptase ribonuclease H domain	JOURNAL OF MEDICINAL CHEMISTRY	2015

Progetti di Ricerca

Progettazione e sintesi di esteri fenil-etil-imidazolici come nuovi inibitori del CYP51 di Naegleria fowleri, attivi nella meningoencefalite amebica primaria (PAM)
Multitarget directed ligands approach per lo sviluppo di nuovi potenziali agenti nella terapia del morbo di Alzheimer.
Sviluppo di nuovi multitarget directed ligands come potenziali agenti nella terapia del morbo di Alzheimer.