Bruno Botta | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Editorial: Secondary Metabolites and Peptides as Unique Natural Reservoirs of New Therapeutic Leads for Treatment of Cancer and Microbial Infections	FRONTIERS IN CHEMISTRY	2021
Exploring the assembly of resorc[4]arenes for the construction of supramolecular nano-aggregates	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2021
Calixarene: a versatile scaffold for the development of highly sensitive biosensors	SUPRAMOLECULAR CHEMISTRY	2021
Identification of effective anticancer g-quadruplex-targeting chemotypes through the exploration of a high diversity library of natural compounds	PHARMACEUTICS	2021
Anti-Candida albicans biofilm activity of extracts from two selected indigenous Algerian plants. Clematis flammula and Fraxinus angustifolia	JOURNAL OF HERBAL MEDICINE	2020
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present)	EXPERT OPINION ON THERAPEUTIC PATENTS	2020
Cannabis sativa L. inflorescences from monoecious cultivars grown in central Italy: an untargeted chemical characterization from early flowering to ripening	MOLECULES	2020
The Pictet-Spengler reaction updates its habits	MOLECULES	2020
Structural elucidation and antimicrobial characterization of novel diterpenoids from fabiana densa var. ramulosa	ACS MEDICINAL CHEMISTRY LETTERS	2020
Site-directed antibodies immobilization by resorc[4]arene-based immunosensors	CHEMISTRY-A EUROPEAN JOURNAL	2020
The revaluation of plant-derived terpenes to fight antibiotic-resistant Infections	ANTIBIOTICS	2020
Improved identification of phytocannabinoids using a dedicated structure-based workflow	TALANTA	2020
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors	JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY	2020
Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections	MOLECULES	2020
Ent-beyerane diterpenes as a key platform for the development of arnt-mediated colistin resistance inhibitors	JOURNAL OF ORGANIC CHEMISTRY	2020
Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: synthesis, cytotoxicity, lipophilicity and molecular docking studies	BIOORGANIC CHEMISTRY	2020
Dual smo/braf inhibition by flavonolignans from silybum marianum†	ANTIOXIDANTS	2020
Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells	CELL DEATH DISCOVERY	2020
Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities	MOLECULES	2020
P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation	THE FASEB JOURNAL	2019

ERC

LS4_12
PE5
PE5_16
PE5_17

KET

Nanotecnologie
Life-science technologies & biotechnologies
Sustainable technologies & development

Interessi di ricerca

Isolamento, caratterizzazione di prodotti naturali da piante. Semisintesi e sintesi totale di prodotti naturali. Sintesi di macrocicli resorc[4]arenici e applicazioni. Funzionalizzazione di nanotubi di carbonio con macrocicli per applicazioni di biosensoristica. Chimica dei cannabinoidi e prodotti estratti dalla Cannabis.

Keywords

chimica

BASI BIOLOGICHE DEL CANCRO

organic chemistry

prodotti naturali

Multiwalled carbon nanotubes (MWCNTs)

biosensing

calixarene

Resorc[4]arene

Gruppi di ricerca - Responsabile

Botta Lab