Bruno Botta

Pubblicazioni

Titolo Pubblicato in Anno
Editorial: Secondary Metabolites and Peptides as Unique Natural Reservoirs of New Therapeutic Leads for Treatment of Cancer and Microbial Infections FRONTIERS IN CHEMISTRY 2021
Exploring the assembly of resorc[4]arenes for the construction of supramolecular nano-aggregates INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Calixarene: a versatile scaffold for the development of highly sensitive biosensors SUPRAMOLECULAR CHEMISTRY 2021
Identification of effective anticancer g-quadruplex-targeting chemotypes through the exploration of a high diversity library of natural compounds PHARMACEUTICS 2021
Anti-Candida albicans biofilm activity of extracts from two selected indigenous Algerian plants. Clematis flammula and Fraxinus angustifolia JOURNAL OF HERBAL MEDICINE 2020
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) EXPERT OPINION ON THERAPEUTIC PATENTS 2020
Cannabis sativa L. inflorescences from monoecious cultivars grown in central Italy: an untargeted chemical characterization from early flowering to ripening MOLECULES 2020
The Pictet-Spengler reaction updates its habits MOLECULES 2020
Structural elucidation and antimicrobial characterization of novel diterpenoids from fabiana densa var. ramulosa ACS MEDICINAL CHEMISTRY LETTERS 2020
Site-directed antibodies immobilization by resorc[4]arene-based immunosensors CHEMISTRY-A EUROPEAN JOURNAL 2020
The revaluation of plant-derived terpenes to fight antibiotic-resistant Infections ANTIBIOTICS 2020
Improved identification of phytocannabinoids using a dedicated structure-based workflow TALANTA 2020
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2020
Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections MOLECULES 2020
Ent-beyerane diterpenes as a key platform for the development of arnt-mediated colistin resistance inhibitors JOURNAL OF ORGANIC CHEMISTRY 2020
Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: synthesis, cytotoxicity, lipophilicity and molecular docking studies BIOORGANIC CHEMISTRY 2020
Dual smo/braf inhibition by flavonolignans from silybum marianum† ANTIOXIDANTS 2020
Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells CELL DEATH DISCOVERY 2020
Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities MOLECULES 2020
P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation THE FASEB JOURNAL 2019

ERC

  • LS4_12
  • PE5
  • PE5_16
  • PE5_17

KET

  • Nanotecnologie
  • Life-science technologies & biotechnologies
  • Sustainable technologies & development

Interessi di ricerca

Isolamento, caratterizzazione di prodotti naturali da piante. Semisintesi e sintesi totale di prodotti naturali. Sintesi di macrocicli resorc[4]arenici e applicazioni. Funzionalizzazione di nanotubi di carbonio con macrocicli per applicazioni di biosensoristica. Chimica dei cannabinoidi e prodotti estratti dalla Cannabis.

Keywords

chimica
BASI BIOLOGICHE DEL CANCRO
organic chemistry
prodotti naturali
Multiwalled carbon nanotubes (MWCNTs)
biosensing
calixarene
Resorc[4]arene

Gruppi di ricerca - Responsabile

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