Bruno Botta

Pubblicazioni

Titolo Pubblicato in Anno
Structural elucidation and antimicrobial characterization of novel diterpenoids from fabiana densa var. ramulosa ACS MEDICINAL CHEMISTRY LETTERS 2020
Site-directed antibodies immobilization by resorc[4]arene-based immunosensors CHEMISTRY-A EUROPEAN JOURNAL 2020
The revaluation of plant-derived terpenes to fight antibiotic-resistant Infections ANTIBIOTICS 2020
Improved identification of phytocannabinoids using a dedicated structure-based workflow TALANTA 2020
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2020
Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections MOLECULES 2020
Ent-beyerane diterpenes as a key platform for the development of arnt-mediated colistin resistance inhibitors JOURNAL OF ORGANIC CHEMISTRY 2020
Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: synthesis, cytotoxicity, lipophilicity and molecular docking studies BIOORGANIC CHEMISTRY 2020
Dual smo/braf inhibition by flavonolignans from silybum marianum† ANTIOXIDANTS 2020
Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells CELL DEATH DISCOVERY 2020
Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities MOLECULES 2020
P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation THE FASEB JOURNAL 2019
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia ACS MEDICINAL CHEMISTRY LETTERS 2019
IR ion spectroscopy in a combined approach with MS/MS and IM-MS to discriminate epimeric anthocyanin glycosides (cyanidin 3-O-glucoside and -galactoside) INTERNATIONAL JOURNAL OF MASS SPECTROMETRY 2019
Nigritanine as a new potential antimicrobial alkaloid for the treatment of staphylococcus aureus-induced infections TOXINS 2019
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth CANCERS 2019
Statins interfere with the attachment of S. cerevisiae mtDNA to the inner mitochondrial membrane JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2019
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma CELL COMMUNICATION AND SIGNALING 2019
In Memory of Maurizio Botta: his Contribution to the Development of Computer-Aided Drug Design JOURNAL OF CHEMICAL INFORMATION AND MODELING 2019
Novel 1,3,4-thiadiazole conjugates derived from protocatechuic acid: Synthesis, antioxidant activity, and computational and electrochemical studies COMPTES RENDUS CHIMIE 2019

ERC

  • LS4_12
  • PE5
  • PE5_16
  • PE5_17

KET

  • Nanotecnologie
  • Life-science technologies & biotechnologies
  • Sustainable technologies & development

Interessi di ricerca

Isolamento, caratterizzazione di prodotti naturali da piante. Semisintesi e sintesi totale di prodotti naturali. Sintesi di macrocicli resorc[4]arenici e applicazioni. Funzionalizzazione di nanotubi di carbonio con macrocicli per applicazioni di biosensoristica. Chimica dei cannabinoidi e prodotti estratti dalla Cannabis.

Keywords

chimica
BASI BIOLOGICHE DEL CANCRO
organic chemistry
prodotti naturali
Multiwalled carbon nanotubes (MWCNTs)
biosensing
calixarene
Resorc[4]arene

Gruppi di ricerca - Responsabile

Botta Lab

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