Romano Silvestri

Pubblicazioni

Titolo Pubblicato in Anno
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2017
Computer-aided identification and lead optimization of dual murine double minute 2 and 4 binders: structure-activity relationship studies and pharmacological activity JOURNAL OF MEDICINAL CHEMISTRY 2017
Heterocyclic pharmacochemistry of new rhinovirus antiviral agents: a combined computational and experimental study EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2017
Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo TUMOR BIOLOGY 2016
VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2016
Pro-apoptotic and pro-differentiation induction by 8-quinolinecarboxaldehyde selenosemicarbazone and its Co(III) complex in human cancer cell lines MEDCHEMCOMM 2016
Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2016
New Inhibitors of Dengue Virus Replication Abstract eBook 2016
New Inhibitors of indoleamine 2,3-dioxygenase 1: molecular modelling studies, synthesis and biological evaluation Abstract eBook 2016
New inhibitors of indoleamine 2,3-dioxygenase 1: molecular modeling studies, synthesis, and biological evaluation JOURNAL OF MEDICINAL CHEMISTRY 2016
Structure-based virtual screening to get new scaffold inhibitors of the Ser/Thr protein kinase PknB from Mycobacterium tuberculosis LETTERS IN DRUG DESIGN & DISCOVERY 2016
Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors MOLECULES 2016
New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2015
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents JOURNAL OF MEDICINAL CHEMISTRY 2015
Pharmacological folding chaperones act as allosteric ligands of Frizzled4 NATURE CHEMICAL BIOLOGY 2015
Kinetic characterization of 4,4'-biphenylsulfonamides as selective non-zinc binding MMP inhibitors JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2015
Discovery of 1,1'-biiphenyl-4-sulfonamides as a new class of potent and selective carbonic anhydrase XIV inhibitors JOURNAL OF MEDICINAL CHEMISTRY 2015
Endogenous vs exogenous allosteric modulators in GPCRs: a dispute for shuttling CB1 among different membrane microenvironments SCIENTIFIC REPORTS 2015
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer JOURNAL OF MEDICINAL CHEMISTRY 2015
Poster: "In vivo selection of JARID histone demethylases inhibitors and their use to enlighten the biological role of these enzymes in yeast and mammalian cells with focus on transcriptional regulation” Abstracts of the 27th International Conference on Yeast Genetics and Molecular Biology 2015

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