Pubblicazioni

Modulating undruggable targets to overcome cancer therapy resistance

2022 - DRUG RESISTANCE UPDATES

Passirani, C.; Vessieres, A.; La Regina, G.; Link, W.; Silvestri, R.

Functional In Vitro Assessment of VEGFA/NOTCH2 Signaling Pathway and pRB Proteasomal Degradation and the Clinical Relevance of Mucolipin TRPML2 Overexpression in Glioblastoma Patients

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Santoni, G.; Amantini, C.; Nabissi, M.; Arcella, A.; Maggi, F.; Santoni, M.; Morelli, M. B.

Vemurafenib plus rituximab in refractory or relapsed hairy-cell leukemia

2021 - NEW ENGLAND JOURNAL OF MEDICINE

Tiacci, E.; De Carolis, L.; Simonetti, E.; Capponi, M.; Ambrosetti, A.; Lucia, E.; Antolino, A.; Pulsoni, A.; Ferrari, S.; Zinzani, P. L.; Ascani, S.; Perriello, V. M.; Rigacci, L.; Gaidano, G.; Seta, R. D.; Frattarelli, N.; Falcucci, P.; Foa, R.; Visani, G.; Zaja, F.; Falini, B.

Real-life comparison of nilotinib versus dasatinib as second-line therapy in chronic phase chronic myeloid leukemia patients

2021 - ANNALS OF HEMATOLOGY

Scalzulli, E.; Caocci, G.; Efficace, F.; Rizzo, L.; Colafigli, G.; Di Prima, A.; Pepe, S.; Fegatelli, D. A.; Carmosino, I.; Diverio, D.; Latagliata, R.; La Nasa, G.; Martelli, M.; Foa, R.; Breccia, M.

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells

2019 - TOXICOLOGY AND APPLIED PHARMACOLOGY

Ranjbar, S.; Khonkarn, R.; Moreno, A.; Baubichon-Cortay, H; Miri, R.; Khoshneviszadeh, M.; Saso, L.; Edraki, N.; Falson, P.; Firuzi, O.

Nivolumab as a safe and effective treatment in an HIV patient with refractory Hodgkin lymphoma

2019 - ANNALS OF HEMATOLOGY

Serrao, A.; Canichella, M.; De Luca, M. L.; Tartaglia, G.; Annechini, G.; D'Elia, G. M.; Pulsoni, A.

How to assess drug resistance in cancer stem cells

2018 - Methods in Molecular Biology

De Angelis, Maria Laura; De Maria, Ruggero; Baiocchi, Marta

Molecular basis of drug resistance and insights for new treatment approaches in mCRPC

2018 - ANTICANCER RESEARCH

Giacinti, Silvana; Poti, Giulia; Roberto, Michela; Macrini, Serena; Bassanelli, Maria; Di Pietro, Francesca; Aschelter, Anna Maria; Ceribelli, Anna; Ruggeri, Enzo Maria; Marchetti, Paolo

Treatment in EGFR-mutated non-small cell lung cancer: how to block the receptor and overcome resistance mechanisms

2017 - TUMORI

Proto, Claudia; Lo Russo, Giuseppe; Corrao, Giulia; Ganzinelli, Monica; Facchinetti, Francesco; Minari, Roberta; Tiseo, Marcello; Garassino, Marina Chiara

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

2017 - INTERNATIONAL JOURNAL OF CANCER

Peverelli, E.; Giardino, E.; Treppiedi, D.; Meregalli, M.; Belicchi, M.; Vaira, V.; Corbetta, S.; Verdelli, C.; Verrua, E.; Serban, A. L.; Locatelli, M.; Carrabba, G.; Gaudenzi, G.; Malchiodi, E.; Cassinelli, L.; Lania, A. G.; Ferrero, S.; Bosari, S.; Vitale, G.; Torrente, Y.; Spada, A.; Mantovani, G.

Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

2016 - NUCLEIC ACIDS RESEARCH

Zizza, Pasquale; Cingolani, Chiara; Artuso, Simona; Salvati, Erica; Rizzo, Angela; D'Angelo, Carmen; Porru, Manuela; Pagano, Bruno; Amato, Jussara; Randazzo, Antonio; Novellino, Ettore; Stoppacciaro, Antonella; Gilson, Eric; Stassi, Giorgio; Leonetti, Carlo; Biroccio, Annamaria

Critical concepts, practice recommendations, and research perspectives of pixantrone therapy in non-Hodgkin lymphoma: a SIE, SIES, and GITMO consensus paper

2016 - EUROPEAN JOURNAL OF HAEMATOLOGY

Zinzani, Pier Luigi; Corradini, Paolo; Martelli, Maurizio; Minotti, Giorgio; Oliva, Stefano; Spina, Michele; Barosi, Giovanni; Tura, Sante

Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis

2016 - LIFE SCIENCES

Sestito, Rosanna; Cianfrocca, Roberta; RosanÃ², Laura; Tocci, Piera; Di Castro, Valeriana; Caprara, Valentina; Bagnato, Anna

miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma

2016 - ONCOTARGET

Sestito, Rosanna; Cianfrocca, Roberta; RosanÃ², Laura; Tocci, Piera; Semprucci, Elisa; Di Castro, Valeriana; Caprara, Valentina; Ferrandina, Gabriella; Sacconi, Andrea; Blandino, Giovanni; Bagnato, Anna

Daratumumab, bortezomib, and dexamethasone for multiple myeloma

2016 - NEW ENGLAND JOURNAL OF MEDICINE

Palumbo, Antonio; Chanan Khan, Asher; Weisel, Katja; Nooka, Ajay K.; Masszi, Tamas; Beksac, Meral; Spicka, Ivan; Hungria, Vania; Munder, Markus; Mateos, Maria V.; Mark, Tomer M.; Qi, Ming; Schecter, Jordan; Amin, Himal; Qin, Xiang; Deraedt, William; Ahmadi, Tahamtan; Spencer, Andrew; Sonneveld, Pieter; Foa, Roberto; Castor, Investigators

Endocrine therapy in post-menopausal women with metastatic breast cancer: From literature and guidelines to clinical practice

2016 - CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Sini, Valentina; Cinieri, Saverio; Conte, Pierfranco; De Laurentiis, Michelino; Leo, Angelo Di; Tondini, Carlo; Marchetti, Paolo

Splenic marginal zone lymphoma : Prognostic factors ,role of watch and wait policy ,and othert herapeutic approaches in the rituximab era

2016 - EXPERT REVIEW OF HEMATOLOGY

Capria, Saveria; Barberi, Walter; Perrone, Salvatore; Ferretti, Antonietta; Salaroli, Adriano; Annechini, Giorgia; DâElia, Gianna Maria; FoÃ , Robin; Pulsoni, Alessandro

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

2015 - BIOCHEMICAL PHARMACOLOGY

Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria

Clinical features and outcome of SIL/TAL1-positive t-cell acute lymphoblastic leukemia in children and adolescents: A 10-year experience of the AIEOP group

2015 - HAEMATOLOGICA

D'AngiÃ², M; Valsecchi, Mg; Testi, Anna Maria; Conter, V; Nunes, Vittorio; Parasole, R; Colombini, A; Santoro, N; Varotto, S; Caniglia, M; Silvestri, D; Consarino, C; Levati, L; Magrin, E; Locatelli, F; Basso, G; Foa, Roberto; Biondi, A; Cazzaniga, G.

An overview of early investigational therapies for chemoresistant ovarian cancer

2015 - EXPERT OPINION ON INVESTIGATIONAL DRUGS

Marchetti, Claudia; Ledermann, Jonathan A.; BENEDETTI PANICI, Pierluigi

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs)

2015 - ONCOTARGET

Prasetyanti, Pramudita R.; Capone, Emily; Barcaroli, Daniela; D'Agostino, Daniela; Volpe, Silvia; Benfante, Antonina; van Hooff, Sander; Iacobelli, Valentina; Rossi, Cosmo; Iacobelli, Stefano; Medema, Jan Paul; de Laurenzi, Vincenzo; Sala, Gianluca