Pubblicazioni

RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo

2023 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sebastiani, J.; Puxeddu, M.; Nalli, M.; Bai, R.; Altieri, L.; Rovella, P.; Gaudio, E.; Trisciuoglio, D.; Spriano, F.; Lavia, P.; Fionda, C.; Masci, D.; Urbani, A.; Bigogno, C.; Dondio, G.; Hamel, E.; Bertoni, F.; Silvestri, R.; La Regina, G.

Human estrogen receptor Î± antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kurtanovic, N.; Tomasevic, N.; Matic, S.; Mitrovic, M. M.; Kostic, D. A.; Sabatino, M.; Antonini, L.; Ragno, R.; Mladenovic, M.

Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia

2021 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Puxeddu, M.; Shen, H.; Bai, R.; Coluccia, A.; Bufano, M.; Nalli, M.; Sebastiani, J.; Brancaccio, D.; Da Pozzo, E.; Tremolanti, C.; Martini, C.; Orlando, V.; Biagioni, S.; Sinicropi, M. S.; Ceramella, J.; Iacopetta, D.; Coluccia, A. M. L.; Hamel, E.; Liu, T.; Silvestri, R.; La Regina, G.

Novel N-aryl nicotinamide derivatives: Taking stock on 3,6-diazabicyclo[3.1.1]heptanes as ligands for neuronal acetylcholine receptors

2019 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Murineddu, G; Gotti, C; Asproni, B; Corona, P; Martinello, K; Plutino, S; Fucile, S; Temml, V; Moretti, M; Viani, P; Schuster, D; Piras, S; Deligia, F; Pinna, GA

Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for Î±4Î²2nACh receptors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Deligia, Francesco; Murineddu, Gabriele; Gotti, Cecilia; Ragusa, Giulio; Fasoli, Francesca; Sciaccaluga, Miriam; Plutino, Simona; Fucile, Sergio; Loriga, Giovanni; Asproni, Battistina; Pinna, Gerard A