Ricerc@Sapienza

The advanced artificial intelligence assisted endoscopic workstation will be constituted by last generation gastroscope, colonoscope, duodenoscope, cholangioscope, endoscopic ultrasound probe equipped with softwares to improve images and artificial intelligence. The workstation will be used 1) to detect and characterize benign and malignant gastrointestinal lesions, assess malignant lesion depth of invasion and establish the optimal management, 2) to develop a platform for autologous organoid creation for the liver regenerative medicine, and for the personalized medicine of liver diseases, and to develop a platform for overcoming the lack of renewable sources of human cells for the transplant-based treatment of liver diseases and diabetes based on autologous stem cells isolated from endoscopic biopsies. The research lines that will benefit from the integrated platform (workstation) are of a clinical, endoscopic, radiological and translational nature. Range of users go from surgeons, clinicians, radiologists, to anatomists and basic scientists. Five big Medical, Surgical, Diagnostic and Basic/Translational Discipline Departments governing two big "Sapienza'' medical poles, the Policlinico Umberto I of Rome and the Polo Pontino in Latina, within the Sapienza Health Hub, are involved in an integrated and systematic way in this project, for clinical reasons and for develop translational research lines. The same workstation will be largely used for further collaborative multicenter validation and follow-up studies within existing international research networks. Furthermore, constituting an almost unique instrument of its kind, will favor scientific excellence and the attractiveness of "Sapienza" University of Rome, both nationally and internationally. Finally, may also play an important role in completing a high-level specialist training, both for students, postgraduates, doctoral students and postdocs.