Progetti di ricerca
| Titolo del progetto | Anno | Proponente | Abstract | ERC | Keywords | Struttura |
|---|---|---|---|---|---|---|
| Prediction of life-threatening ventricular arrhythmia in patients with hypertrophic cardiomyopathy: role of three-dimensional architecture of scar conducting channels assessed with high resolution cardiac magnetic resonance | 2021 | Pietro Francia |
Myocardial scar is a common finding in patients with hypertrophic cardiomyopathy (HCM) and provides the substrate for ventricular arrhythmia (VA). |
LS4_7, LS7_1 | CARDIOLOGIA, FISIOLOGIA CARDIOCIRCOLATORIA, MALATTIE RARE | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Ferroptosis: correlation between STK11-KEAP1 mutations and lipid metabolism in Lung Cancer Stem Cells (LCSCs). | 2021 | Rita Mancini |
Lung cancer is the leading cause of cancer mortality. |
LS4_6, LS2_15, LS1_10 | BASI BIOLOGICHE DEL CANCRO, BIOLOGIA DELLE CELLULE STAMINALI, METABOLISMO LIPIDICO, MEDICINA MOLECOLARE, GENOMICA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| NOTCH3 pathogenic variants in multiple sclerosis patients: frequency, clinical features and disease-associated cellular phenotypes | 2021 | Simona Petrucci |
Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) leading to inflammatory lesion in brain and spinal cord. |
LS2_1, LS5_7 | GENETICA MEDICA, NEUROLOGIA, GENETICA MOLECOLARE, NEURORADIOLOGIA, PATOLOGIA GENERALE | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Pharmacological intervention to target the pro-calcific phenotypic drift of myeloid cells: a pilot study | 2021 | Carmen Mignogna |
Background: Cardiovascular disease (CVD) is the major cause of morbidity and mortality in subjects with type 2 diabetes (T2D). |
LS4_3 | DIABETE, ATEROSCLEROSI, MEDICINA MOLECOLARE | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Sintesi e caratterizzazione di nanomateriali per applicazioni in biotecnologia e sensoristica. | 2021 | Tommaso Alberto Salamone |
I materiali nanostrutturati trovano impiego in diversi ambiti, quali l'optoelettronica, la sensoristica, la catalisi, la nanomedicina. |
PE5_6, PE5_10, PE5_8 | NANOPARTICELLE, NANOMATERIALI, CHIMICA DELLE SUPERFICI, BIOMATERIALI, NANOTECNOLOGIE | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Risposta immunologica al vaccino SARS-CoV-2 in soggetti affetti da diabete mellito. Studio CoVaDiab (Sars-Cov2 Vaccine & Diabetes) | 2021 | Luca D'Onofrio |
Il diabete mellito è tra le principali patologie che costituiscono un fattore prognostico negativo in corso di infezione da SARS-Cov-2 per gli esiti negativi della malattia Covid-19. |
LS4_3, LS4_5, LS6_7 | DIABETE, VIROLOGIA, VACCINOLOGIA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Molecular characterization of mediastinal and non-mediastinal nodular sclerosis classical Hodgkin lymphoma to unveil potentially distinct disease entities | 2021 | Arianna Di Napoli |
Nodular sclerosis classical Hodgkin lymphoma (NSCHL) is a subtype of CHL affecting young adults and manifesting either with a systemic nodal disease or alternatively with a mediastinal mass. |
LS4_6, LS2_8, LS6_4 | MEDICINA MOLECOLARE, BASI BIOLOGICHE DEL CANCRO, EMATOLOGIA, ANATOMIA PATOLOGICA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Role of gut microbiome and TMAO microbial metabolite in plaque instability. | 2021 | Riccardo Nieri |
Ischemic disease is currently the most important cause of heart failure, which is considered a major public health problem. |
LS6_5, LS3_4, LS3_5 | ATEROSCLEROSI, MICROBIOTA UMANO, TRAPIANTO | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Comparative transcriptomic and metabolic profiling identification a novel targets of lung Cancer Stem Cells | 2021 | Claudia De Vitis |
Cancer stem cells (CSCs) are the leading cause of cancer initiation, metastasis and chemoresistance, thus eliminating them could lead to permanent cancer eradication. |
LS4_6, LS2_8, LS2_10 | BASI BIOLOGICHE DEL CANCRO, METABOLISMO LIPIDICO, TRASCRITTOMICA, BIOLOGIA MOLECOLARE E INTERAZIONI, BIOLOGIA CELLULARE | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| ALTAIR PROTOCOL: ALTo endogrAft Italian Registry | 2021 | Maurizio Taurino |
The aim of present study is to evaluate intraoperative, peri-operative, and post-operative results in patients treated by the ALTO stent graft for elective AAA repair in a multicentric consecutive |
LS7_7, LS7_10 | CHIRURGIA VASCOLARE, ATEROSCLEROSI, INVECCHIAMENTO | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |