Progetti di ricerca
| Titolo del progetto | Anno | Proponente | Abstract | ERC | Keywords | Struttura |
|---|---|---|---|---|---|---|
| Role of microRNA in Prostate cancer Diagnosis and Progression | 2021 | Andrea Vecchione |
Cancer of the prostate is now recognized as one of the most important medical problems facing the male population. |
LS2_2, LS7_2, LS2_14 | ANATOMIA PATOLOGICA, BASI BIOLOGICHE DEL CANCRO, BIOLOGIA MOLECOLARE E INTERAZIONI | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Ruolo di varianti di geni codificanti per fattori dell'autofagia nello sviluppo di ipertrofia cardiaca associata all'ipertensione arteriosa nell'uomo: un approccio caso-controllo. | 2021 | Giuliano Tocci |
Il processo di ipertrofia e rimodellamento cardiaco, frequente complicanza dell¿ipertensione arteriosa, è alla base della comune condizione di scompenso cardiaco. |
LS4_7 | CARDIOLOGIA, MEDICINA MOLECOLARE, BIOLOGIA CELLULARE | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Oxidative stress and mitochondrial dysfunction in critical limb ischemia: the relevance of circulating leukocytes. | 2021 | Salvatore Raffa |
Critical limb ischemia (CLI) of the lower extremities is a severe form of peripheral arterial disease (PAD) characterized by a markedly reduces blood flow supply to the legs. |
LS4_1, LS7_3, LS4_7 | ATEROSCLEROSI, STRUMENTAZIONE E METODI DIAGNOSTICI, MEDICINA PERSONALIZZATA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| The challenge of genotype positive-phenotype negative hypertrophic cardiomyopathy: role of a multimodality functional assessment. | 2021 | Damiano Magri' |
Hypertrophic cardiomyopathy (HCM) represents the most common genetic heart disease, inherited with an autosomal dominant pattern, incomplete penetrance and variable expressivity. |
LS4_7 | CARDIOLOGIA, FISIOLOGIA CARDIOCIRCOLATORIA, TECNICHE DI IMAGING, GENETICA MEDICA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Morphological and hormonal characterization of adrenal lesions in the oncological population. | 2021 | Antonio Stigliano |
Nodular adrenal disease is a frequent occurrence in common clinical practice. |
LS4_1, LS7_1, LS7_3 | ENDOCRINOLOGIA, CANCRO, STRUMENTAZIONE E METODI DIAGNOSTICI, DIAGNOSTICA PER IMMAGINI, MEDICINA NUCLEARE E RADIOTERAPIA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Metabolism and mechanism of the new agent CPX-351 for the treatment of acute myeloid leukemia: a novel approach to overcome leukemia resistance. | 2021 | Simone Mirabilii |
Acute Myeloid Leukemia (AML) is the most frequent malignant myeloid disease in the adult population. |
LS4_6, LS7_4 | METABOLISMO, EMATOLOGIA, CANCRO | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Nutrient-induced carbonyl stress as mediator of the cardiometabolic risk linked to unhealthy modern diet | 2021 | Stefano Menini |
Increased consumption of calorie-dense foods is leading to an epidemic of cardiometabolic conditions including diabetes and cardiovascular disease. |
LS4_5, LS4_7, LS4_3 | ALIMENTAZIONE, MALATTIE METABOLICHE, BASI MOLECOLARI E CELLULARI DEI DIFETTI DEL METABOLISMO | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| Prognostic Value of Regional Layer-specific Myocardial 2D Strain Echocardiography and Cardiac Biomarkers for Early Detection of Epirubicin-Related Cardiac Toxicity in Patients Affected by Breast Cancer. | 2021 | Allegra Battistoni |
The development of tools for the early identification of patients at greater risk of cancer therapy-related cardiac dysfunction and heart failure is an area of active research in cardio-oncology. |
LS4_7, LS4_8, LS7_1 | CARDIOLOGIA, CHEMIOTERAPIA, FISIOLOGIA CARDIOCIRCOLATORIA | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| MicroRNAs as biomarkers of bone quality and response to exercise in patients with type 2 diabetes | 2021 | Jonida Haxhi |
Type 2 diabetes (T2D) mellitus is associated with an increased fracture risk, independently of bone mineral density (BMD). A reduction in bone quality might explain this discrepancy in T2D. |
LS4_5, LS2_2 | DIABETE, OSTEOPOROSI, BIOCHIMICA E BIOLOGIA MOLECOLARE CLINICA, BIOCHIMICA GENERALE E METABOLISMO | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |
| FGFR isoform switch in pancreatic ductal adenocarcinoma: role of FGFR2c aberrant expression and signaling in the establishment of EMT and dysregulated autophagy. | 2021 | Francesca Belleudi |
Pancreatic ductal adenocarcinoma (PDAC) is a treatment-resistant malignancy driven by the "undruggable", constitutively active KRAS, which made the search for new therapeutic strategies bypassing t |
LS4_6, LS3_5, LS1_10 | RECETTORI DI MEMBRANA, BASI BIOLOGICHE DEL CANCRO, TRASDUZIONE DEI SEGNALI | DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE |