Alessandro Paiardini

Pubblicazioni

Titolo Pubblicato in Anno
L- Arginine in Pseudomonas aeruginosa controls c-di-GMP levels and biofilm formation efb 2021 2021
Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer ONCOGENE 2021
Phosphorylation, mg‐adp, and inhibitors differentially shape the conformational dynamics of the a‐loop of aurora‐a BIOMOLECULES 2021
Pha-680626 is an effective inhibitor of the interaction between aurora-a and n-myc INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
From parp1 to tnks2 Inhibition: a structure-based approach ACS MEDICINAL CHEMISTRY LETTERS 2020
Artemisinin derivatives with antimelanoma activity show inhibitory effect against human dna topoisomerase 1 ACS MEDICINAL CHEMISTRY LETTERS 2020
SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase EMBO REPORTS 2020
A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome DERMATOLOGY ONLINE JOURNAL 2020
Insights into pparγphosphorylation and its inhibition mechanism JOURNAL OF MEDICINAL CHEMISTRY 2020
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity CELL DEATH & DISEASE 2020
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1 CELL REPORTS 2020
A single center retrospective review of patients from central italy tested for melanoma predisposition genes INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
PyMod 3: a complete suite for structural bioinformatics in PyMOL BIOINFORMATICS 2020
Structure and function of HD-GYP phosphodiesterases Microbial Cyclic Di-Nucleotide Signaling 2020
A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome DERMATOLOGY ONLINE JOURNAL 2020
The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism NUCLEIC ACIDS RESEARCH 2019
N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia FRONTIERS IN ONCOLOGY 2019
A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies MOLECULAR GENETICS AND METABOLISM 2019
R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features THE FEBS JOURNAL 2019
Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy-Walker malformation. MOLECULAR GENETICS & GENOMIC MEDICINE 2019

ERC

  • LS1
  • LS1_8
  • LS1_12
  • LS1_14
  • LS2_11

KET

  • Big data & computing
  • Life-science technologies & biotechnologies

Interessi di ricerca

Bioinformatics, Computational Biology, Medicinal Chemistry, Drug Design, Protein Structure Prediction, Deep Learning, GUI programming, Python, Cancer, Kinases

Progetti di Ricerca

Gruppi di ricerca

Nutrient sensing and redox transducers in bacterial biofilm.

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